Active ingredient combinations comprising pyridylethylbenzamides and other active ingredients

ABSTRACT

The present invention relates to novel active ingredient combinations which consist of fluopyram and other known active ingredients and are very well suited for the control of animal pests, such as insects and/or unwanted acarids and/or nematodes, in foliar and soil application and/or in the treatment of seeds, and are also suitable for increasing yields.

CROSS REFERENCE TO RELATED APPLICATIONS

This application is a Divisional of U.S. patent application Ser. No.15/845,262, filed 18 Dec. 2017, which is a Divisional of U.S. patentapplication Ser. No. 13/990,586, filed 18 Sep. 2013 (now U.S. Pat. No.9,872,494, issued 23 Jan. 2018), which is a National Stage ofPCT/EP2011/071418, filed 30 Nov. 2011, which claims priority to U.S.Provisional Application No. 61/419,438, filed 3 Dec. 2010, and EuropeanPatent Application No. 10193335.6, filed 1 Dec. 2010. The contents ofeach of these applications is hereby incorporated by reference.

The present invention relates to new active ingredient combinationswhich consist of fluopyram and other known active ingredients and whichare very well suited to the control of animal pests, such as insectsand/or unwanted acarids and/or nematodes, in foliar and soil applicationand/or in seed treatment, and also to the boosting of yields.

It is already known that certain pyridylethylbenzamides possessfungicidal, insecticidal, and acaricidal and nematicidal properties.

WO 2004/016088 describes pyridylethylbenzamides and their use asfungacides. The possibility of combining one or more of the disclosedpyridylethylbenzamide derivatives with other known fungicides,insecticides, nematicides or acaricides for the purpose of broadeningthe spectrum of activity is likewise described. The application,however, teaches neither which insecticidal mixing partners aresuitable, nor the mixing ratio in which insecticides andpyridylethylbenzamide derivatives are combined with one another. WO2005/077901 teaches fungicidal compositions comprising at least onepyridylethylbenzamide, a fungicide and an inhibitor of electrontransport in the respiratory chain of fungi. The patent application,however, does not mention any mixtures of pyridylethylbenzamides withinsecticides. WO 2008/003738 teaches fungicidal compositions comprisingat least one pyridylethylbenzamide and an insecticide. A possiblenematicidal action of the compositions is described in the application,but not explicitly for mixtures comprisingN-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide.

The activity of the active ingredients and active ingredientcompositions described in the prior art is good, but is capable ofimprovement at low application rates in certain cases, especially in thecontext of nematode control.

The object on which the present invention is based, therefore, is thatof providing nematicidal, insecticidal and acaricidal active ingredientcombinations having improved activity, especially with regard tonematodes.

It has now been found that active ingredient combinations comprising

-   (I-1)    N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide    of formula (I) (fluopyram)

and also its N-oxides;

and

-   (II) at least one further active ingredient selected from the group    consisting of fluensulfone (II-1), imicyafos (II-2), Bacillus    subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™)    (II-4), Paecilomyces lilacinus (II-5), Paecilomyces lilacinus strain    251 (Bioact™) (II-6), azadirachtin (II-7), thymol (II-8),    Metarhizium anisopliae (II-9), Rhizobium spp. (II-10), Beauverin    spp. (II-11), Verticillium spp. (II-12), Metschnikowia fructicola    (II-13), Metschnikowia fructicola strain NRRL Y-30752, (II-14),    Bacillus subtilis strain GB03 (II-15), Bacillus pumilus strain GB34    (II-16), Bacillus pumilus strain QST2808 (II-17), Bacillus    amyloliquefaciens strain IN937a (II-18), Bacillus amyloliquefaciens    strain FZB 42 (II-19), Myrothecium verrucaria strain AARC-0255    (II-20), pyrethrum (II-21), Cydia pomonella granulosis virus (CpGV)    (II-22), Metarhizium anisopliae strain F52 (II-23), arbuscular    mycorrhiza fungus (II-24), Beauveria bassiana strain ATCC 74040    (II-25), Beauveria brongniartii (II-26), Lecanicillium lecanii (also    known as Verticillium lecanii) (II-27), Bacillus thuringiensis    subsp. tenebrionis (11-28)    are very well suited to the control of phytopathogenic fungi and    animal pests, more particularly nematodes, in foliar and soil    application, particularly in the context of seed treatment, and also    to the boosting of yields.

The insecticides or active nematicidal ingredients of group (II) areselected from the group consisting of the following:

fluensulfone (II-1) known from WO-A 2001/002378and/orimicyafos (II-2) known from EP-A 0464830and/orBacillus subtilis (II-3)and/orBacillus subtilis strain QST 713 (II-4)and/orPaecilomyces lilacinus (II-5)and/orPaecilomyces lilacinus strain 251 (II-6)and/orazadirachtin (Cas-No 11141-17-6) (II-7)and/or

Thymol (II-8)

and/orMetarhizium anisopliae (II-9),and/or

Rhizobium spp. (II-10),

and/or

Beauveria spp. (II-11),

and/or

Verticillium spp (II-12)

and/orMetschnikowia fructicola (II-13) known from Kurztman and Droby, System.Application Microbiol. (2001), 24, pp 395-399and/orMetschnikowia fructicola strain NRRL Y-30752, (II-14) known from U.S.Pat. No. 6,994,849 B2and/orBacillus subtilis strain GB03 (II-15) known under the name Kodiak™marketed by Gustafson LLCand/orBacillus pumilus strain GB34 known under the name YieldShield™ marketedby Gustafson LLCand/orBacillus pumilus strain QST2808 known under the name Sonata™ marketed byAgraquestand/orBacillus amyloliquefaciens strain IN937aand/orMyrothecium verrucaria strain AARC-0255 known under the name DiTera™marketed by Valent Biosciencesand/orpyrethrum (II-21)and/orCydia pomonella granulosis virus (CpGV) (II-22)and/orMetarhizium anisopliae strain F52 (II-23)and/orarbuscular mycorrhiza fungus (II-24)and/orBeauveria bassiana strain ATCC 74040 (known under the name Naturalis®)(II-25)and/orBeauveria brongniartii (II-26)and/orLecanicillium lecanii (formerly known as Verticillium lecanii) (II-27)and/orBacillus thuringiensis subsp. tenebrionis (II-28).

In one preferred embodiment of the invention the active ingredients ofgroup (II) are selected from the group consisting of fluensulfone(II-1), imicyafos (II-2), Bacillus subtilis (II-3), Bacillus subtilisstrain QST 713 (Serenade™) (II-4), Paecilomyces lilacinus (II-5),Paecilomyces lilacinus strain 251 (Bioact™) (II-6), azadirachtin (II-7),thymol (II-8), Metarhizium anisopliae (II-9), Rhizobium spp. (II-10),Beauveria spp. (II-11), Verticillium spp. (II-12), Metschnikowiafructicola (II-13), Metschnikowia fructicola strain NRRL Y-30752,(II-14).

In one preferred embodiment of the invention the active ingredients ofgroup (II) are selected from the group of bacteria consisting ofBacillus subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™)(II-4), Bacillus subtilis strain GB03 (II-15), Bacillus pumilus strainGB34 (II-16), Bacillus pumilus strain QST2808 (II-17), Bacillusamyloliquefaciens strain IN937a (II-18), Rhizobium spp. (II-10),Bacillus thuringiensis subsp. tenebrionis (II-28).

In one preferred embodiment of the invention the active ingredients ofgroup (II) are selected from the group of Bacillus species consisting ofBacillus subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™)(II-4), Bacillus subtilis strain GB03 (II-15), Bacillus pumilus strainGB34 (II-16), Bacillus pumilus strain QST2808 (II-17), Bacillusamyloliquefaciens strain IN937a (II-18), Bacillus thuringiensis subsp.tenebrionis (II-28).

In one preferred embodiment of the invention the active ingredients ofgroup (II) are selected from the group of fungal species consisting ofPaecilomyces lilacinus (II-5), Paecilomyces lilacinus strain 251(Bioact™) (II-6), Metarhizium anisopliae (II-9), Beauveria spp. (II-11),Verticillium spp. (II-12), Metschnikowia fructicola (II-13),Metschnikowia fructicola strain NRRL Y-30752, (II-14), Myrotheciumverrucaria strain AARC-0255 (II-19), Metarhizium anisopliae strain F52(II-23), arbuscular mycorrhiza fungus (II-24), Beauveria bassiana, inparticular strain ATCC 74040 (II-25), Beauveria brongniartii (II-26),Lecanicillium lecanii (formerly known as Verticillium lecanii) (II-27).

In one preferred embodiment of the invention the active ingredients ofgroup (II) are selected from the group consisting of fluensulfone(II-1), imicyafos (II-2), Paecilomyces lilacinus (II-5), Paecilomyceslilacinus strain 251 (Bioact™) (II-6), Metarhizium anisopliae (II-9),Metschnikowia fructicola (II-13), Metschnikowia fructicola strain NRRLY-30752, (II-14), Bacillus subtilis strain GB03 (II-15), Bacillusamyloliquefaciens strain FZB 42 (II-19), Bacillus thuringiensis subsp.tenebrionis (II-28), pyrethrum (II-21), Cydia pomonella granulosis virus(CpGV) (II-22), Metarhizium anisopliae strain F52 (II-23), arbuscularmycorrhiza fungus (II-24).

In one preferred embodiment of the invention the active ingredients ofgroup (II) are selected from the group consisting of fluensulfone(II-1), imicyafos (II-2), Bacillus subtilis (II-3), Bacillus subtilisstrain QST 713 (Serenade™) (II-4), Paecilomyces lilacinus (II-5),Paecilomyces lilacinus strain 251 (Bioact™) (II-6) and alsoMetschnikowia fructicola (II-13).

In one particularly preferred embodiment of the invention the activeingredients of group (II) are selected from the group consisting offluensulfone (II-1), imicyafos (II-2), Bacillus subtilis strain QST 713(Serenade™) (II-4), Paecilomyces lilacinus strain 251 (Bioact™) (II-6).

In one preferred embodiment of the invention the active ingredients ofgroup (II) are selected from the group of the low molecular mass activeingredients fluensulfone (II-1), imicyafos (II-2), azadirachtin (II-7),thymol (II-8).

Surprisingly, the fungicidal, insecticidal and/or acaricidal and/ornematicidal action, more particularly the nematicidal action, of theactive ingredient combinations of the invention, particularly after sodapplication, is substantially higher than the sum of the actions of theindividual active ingredients. The effect is an unpredictable truesynergistic effect, and not merely a supplementation of action.Moreover, the active ingredient combinations of the invention aresuitable for effecting a boost to yield.

Preferred active ingredient combinations are those comprising thecompounds of the formula (I-1) and at least one active ingredient of theformula (II).

Of particular interest are the following combinations:

(I-1)+(II-1), (I-1)+(II-2), (I-1)+(II-3), (I-1)+(II-4), (I-1)+(II-5),(I-1)+(II-6), (I-1)+(II-7), (I-1)+(II-8), (I-1)+(II-9), (I-1)+(II-10),(I-1)+(II-11), (I-1)+(II-12), (I-1)+(II-13), (I-1)+(II-14),(I-1)+(II-15), (I-1)+(II-16), (I-1)+(II-17), (I-1)+(II-18),(I-1)+(II-19), (I-1)+(II-20), (I-1)+(II-21), (I-1)+(II-22),(I-1)+(II-23), (1-1)+(II-24), (I-1)+(II-25), (I-1)+(II-26),(I-1)+(II-27), (I-1)+(II-28).

The active ingredient combinations may also, furthermore, compriseother, admix components with fungicidal, acaricidal, nematicidal orinsecticidal activity.

If the active ingredients are present in particular weight ratios in theactive ingredient combinations of the invention, the improved action isapparent with particular clarity. However, within the active ingredientcombinations, the weight ratios of the active ingredients can be variedwithin a relatively wide range. In general the combinations of theinvention comprise active ingredients of the formula (I-1) and themixing partner in the preferred and particularly preferred mixing ratiosindicated in the table below:

Very particularly Mixing Preferred mixing ratio Particularly preferredmixing preferred mixing ratio partner (I-1):Mixing partner ratio(I-1):Mixing partner (I-1):Mixing partner II-1 500:1 to 1:500 125:1 to1:125 25:1 to 1:25 II-2 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-3500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-4 500:1 to 1:500 125:1 to1:125 25:1 to 1:25 II-5 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-6500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-7 500:1 to 1:500 125:1 to1:125 25:1 to 1:25 II-8 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-9500:1 to 1:50000 125:1 to 1:12500 25:1 to 1:2500 II-10 500:1 to 1:500125:1 to 1:125 25:1 to 1:25 II-11 500:1 to 1:500 125:1 to 1:125 25:1 to1:25 II-12 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-13 500:1 to1:500 125:1 to 1:125 25:1 to 1:25 II-14 500:1 to 1:500 125:1 to 1:12525:1 to 1:25 II-15 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-16500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-17 500:1 to 1:500 125:1 to1:125 25:1 to 1:25 II-18 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25II-19 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-20 500:1 to 1:500125:1 to 1:125 25:1 to 1:25 II-21 500:1 to 1:500 125:1 to 1:125 25:1 to1:25 II-22 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-23 500:1 to1:500 125:1 to 1:125 25:1 to 1:25 II-24 500:1 to 1:500 125:1 to 1:12525:1 to 1:25 II-25 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-26500:1 to 1:500 125:1 to 1:125 25:1 to 1:25 II-27 500:1 to 1:500 125:1 to1:125 25:1 to 1:25 II-28 500:1 to 1:500 125:1 to 1:125 25:1 to 1:25

Animal Pests

The active ingredient combinations combine good tolerance by plants withsuitability for controlling animal pests, such as insects and/orarachnids, and more particularly nematodes, which are prevalent inviticulture, fruit growing, agriculture, horticulture, and forestry.They can be used with preference as crop protection compositions. Theyare active against normally sensitive species and resistant species, andalso against all or individual development stages. The aforementionedpests include the following:

Insects

Examples from the order of the Anoplura (Phthiraptera): Damalinia spp.,Haematopinus spp., Linognathus spp., Pediculus spp., Trichodectes spp.

Examples from the class of the Arachnida: Acarus spp., Aceria sheldoni,Aculops spp., Aculus spp., Amblyomma spp., Amphitetranychus viennensis,Aigas spp., Boophilus spp., Brevipalpus spp., Bryobia praetiosa,Chorioptes spp., Dermanyssus gallinae, Eotetranychus spp., Epitrimeruspyri, Eutetranychus spp., Eriophyes spp., Halotydeus destructor,Hermitarsonemus spp., Hyalomma spp., Ixodes spp., Latrodectus mactans,Metatetranychus spp., Nuphersa spp., Oligonychus spp., Ornithodorosspp., Panonychus spp., Phyllocoptruta oleivora, Polyphagotarsoneinustalus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptesspp., Scorpio maurus, Stenotarsonemus spp., Tarsonemus spp., Tetranychusspp., Vasates lycopersici.

Examples from the class of the Bivalva: Dreissena spp.

Examples from the order of the Chilopoda: Geophilus spp., Scutigera spp.

Examples from the order of the Coleoptera: Acalymma vittatum,Acanthoscelides obtectus, Adoretus spp., Agelastica alni, Agriotes spp.,Amphimallon solstitialis, Anobium punctatum, Anoplophora spp.,Anthonomus spp., Anthrenus spp., Apion spp., Apogonia spp., Atomariaspp., Attagenus spp., Bruchidius obtectus, Bruchus spp., Cassida spp.,Cerotoma trifurcata, Ceutorrhynchus spp., Chaetocnema spp., Cleonusmendicus, Conoderus spp., Cosmopolites spp., Costelytra zealandica,Ctenicera spp. Curculio spp., Cryptorhynchus lapathi, Cylindnocopturusspp., Dermestes spp., Diabrotica spp., Dichocrocis spp., Diloboderusspp., Epilachna spp., Epitrix spp., Faustinus spp., Gibbium psylloides,Hellula undalis, Heteronychus arator, Heteronyx spp., Hylamorphaelegans, Hylotrupes bajulus, Hypera postica, Hypothenemus spp.,Lachnosterna consanguinea, Lema spp., Leptinotarsa decernlineata,Leucoptera spp., Lissorhoptrus oryzophilus, Lixus spp., Luperodes spp.,Lyctus spp., Megascelis spp., Melanotus spp., Meligethes aeneus,Melolontha spp., Migdolus spp., Monochamus spp., Naupactusxanthographus, Niptus hololeucus, Oryctes rhinoceros, Oryzaephilussurinamensis, Otyzaphagus oryzae, Otiorrhynchus spp., Oxycetoniajucunda, Phaedon cochleariae, Phyllophaga spp., Phyllotreta spp.,Popilha japonica, Premnotrypes spp., Psylliodes spp., Ptinus spp.,Rhizobius ventralis, Rhizopertha dominica, Sitophilus spp., Sphenophorusspp., Sternechus spp., Symphyletes spp., Tanymecus spp., Tenebriomolitor, Tribolium spp., Trogoderma spp., Tychius spp., Xylotrechusspp., Zabrus spp.

Example from the order of the Collernbola: Onychiurus armatus.

Example from the order of the Diplopoda: Blaniulus guttulatus.

Examples from the order of the Diptera: Aedes spp., Agromyza spp.,Anastrepha spp., Anopheles spp., Asphondylia spp., Bactrocera spp.,Bibio hortulanus, Calliphora erythrocephala, Ceratitis capitata,Chironomus spp., Chrysomyia spp., Cochliomyia spp., Contarinia spp.,Cordylobia anthropophaga, Culex spp., Cuterebra spp., Dacus oleae,Dasyneura spp., Delia spp., Dermatobia horninis, Drosophila spp.,Echinocnemus spp., Fannia spp., Gastrophilus spp., Hydrellia spp.,Hylemyia spp., Hyppobosca spp., Hypoderma spp., Liriomyza spp., Luciliaspp., Musca spp., Nezara spp., Oestrus spp., Oscinella frit, Pegomyiaspp., Phorbia spp., Prodiplosis spp., Psila rosae, Rhagoletis spp.,Stornoxys spp., Tabanus spp., Tannia spp., Tetanops spp., Tipula spp.

Examples from the class of the Gastropoda: Arion spp., Biomphalariaspp., Bulinus spp., Deroceras spp., Galba spp., Lymnaea spp.,Oncomelania spp., Pomaeea spp., Succinea spp.

Examples from the class of the helminths: Ancylostoma duodenale,Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp.,Ascaris lumbricoides, Ascaris spp., Brugia malayi, Brugia timori,Bunostomum spp., Chabertia spp., Clonorchis spp., Cooperia spp.,Dicrocoelium spp, Dictyocaulus filaria, Diphyllobothrium latum,Dracunculus medinensis, Echinococcus granulosus, Echinococcusmultilocularis, Enterobius vernicularis, Faciola spp., Haemonchus spp.,Heterakis spp., Hymenolepis nana, Hyostrongulus spp., Loa Loa,Nematodirus spp., Oesophagostomum spp., Opisthorchis spp., Onchocercavolvulus, Ostertagia spp., Paragonimus spp., Schistosomen spp,Strongyloides fuelleborni, Strongyloides stercoralis, Stronyloides spp.,Taenia saginata, Taenia solium, Trichinella spiralis, Trichinellanativa, Trichinella britovi, Trichinella nelsoni, Trichinellapseudopsiralis, Trichostrongulus spp., Trichuris trichiura, Wuchercriabancrofti.

It is also possible for protozoa, such as Eimeria, to be controlled.

Examples from the order of the Heteroptera: Anasa tristis, Antestiopsisspp., Blissus spp., Calocoris spp., Campylomma livida, Cavelerius spp.,Cimex spp., Collaria spp., Creontiades dilutus, Dasynus piperis,Dichelops furcatus, Diconocoris hewetti, Dysdercus spp., Euschistusspp., Eurygaster spp., Heliopeltis spp., Horcias nobilellus, Leptocorisaspp., Leptoglossus phyllopus, Lygus spp., Macropes excavatus, Miridae,Monalonion atratum, Nezara spp., Oebalus spp., Pentomidae, Piesmaquadrata, Piezodorus spp., Psallus spp., Pseudacysta persea, Rhodniusspp., Sahlbergella singularis, Scaptocoris castanea, Scotinophora spp.,Stephanitis nashi, Tibraca spp., Triatoma spp.

Examples from the order of the Homoptera: Acyrthosipon spp., Acrogoniaspp., Aeneolamia spp., Agonoseena spp., Aleurodes spp., Aleurolobusbarodensis, Aleurothrixus spp., Amrasca spp., Anuraphis cardui.Aonidiella spp., Aphanostigma piri, Aphis spp., Arboridia apicalis,Aspidiella spp., Aspidiotus spp., Atanus spp., Aulacorthum solani,Bemisia spp., Brachycaudus helichrysii, Brachycolus spp., Brevicorynebrassicae, Gilligypona marginata, Cameocephala fulgida, Ceratovaeunalanigera, Cercopidae, Ceroplastes spp., Chaetosiphon fragaefolii,Chionaspis tegalensis, Chlorita onukii, Chromaphis juglandicola.Chrysomphalus ficus, Cicadulina mbila, Coccomytilus halli, Coccus spp.,Cryptomyzus ribis, Daibulus spp., Dialeurodes spp., Diaphorina spp.,Diaspis spp., Drosicha spp., Dysaphis spp., Dysmicoccus spp., Empoascaspp., Eriosoma spp., Erythroneura spp., Euscelis bilobatus, Ferrisiaspp., Geococcus coffeae, Hieroglyphus spp., Homalodisca coagulata,Hyalopterus arundinis, Icerya spp., Idiocerus spp., Idioscopus spp.,Laodelphax striatellus, Lecanium spp., Lepidosaphes spp., Lipaphiserysimi, Macrosiphum spp., Mahanarva spp., Melanaphis sacchari,Metcalfiella spp., Metopolophium dirhodum, Monellia costalis,Monelliopsis pecanis, Myzus spp., Nasonovia ribisnigri, Nephotettixspp., Nilaparvata lugens, Oncometopia spp., Orthezia praelonga,Parabemisia myricae, Paratrioza spp., Parlatoria spp., Pemphigus spp.,Peregrinus maidis, Phenacoceus spp., Phloeomyzus passerinii, Phorodonhuinuli, Phylloxera spp., Pinnaspis aspidisirae, Planococcus spp.,Protopulvinaria pyriformis, Pseudaulacaspis pentagona, Pseudococcusspp., Psylla spp., Pteromalus spp., Pyrilla spp., Quadraspidiotus spp.,Quesada gigas, Rastrococcus spp., Rhopalosiphum spp., Saissetia spp.,Scaphoides titanus, Schizaphis graminum, Selenaspidus articulatus,Sogata spp., Sogatella furcifera, Sogatodes spp., Stictocephala festina,Tenalaphara malayensis, Tinocallis earyaefoliae, Tomaspis spp.,Toxoptera spp., Trialeurodes spp., Trioza spp., Typhkxyba spp., Unaspisspp., Viteus vitifolii, Zygina spp.

Examples from the order of the Hymenoptera: Athalia spp., Diprion spp.,Hoplocampa spp., Lasius spp., Monomorium pharaonis, Vespa spp.

Examples from the order of the Isopoda: Annadillidium vulgare, Oniscusasellus, Porcellio scaber.

Examples from the order of the Isoptera: Acromyrmex spp., Atta spp.,Cornitermes cumulans, Micmtennes obesi, Odontotermes spp.,Reticulitermes spp.

Examples from the order of the Lepidoptera: Acronicta major, Adoxophyesspp., Aedia leucomelas, Agmtis spp., Alabama spp., Amyelois transitella,Anarsm spp., Anticarsia spp., Argyroploce spp., Barathra brassieae,Borbo cinnara, Bucculatrix thurbericlla, Bupalus piniarius, Busseolaspp., Cacoecia spp., Caloptilia theivora, Capua reticulana, Carpocapsapomonella, Caiposina niponensis, Cheimatobia brumata, Chiki spp.,Choristoneura spp., Clysia arnbiguella, Cnaphalocerus spp., Cnephasiaspp., Conopomorpha spp., Conotrachelus spp., Copitarsia spp., Cydiaspp., Dalaca noctuides, Diaphania spp., Diatraea saceharalis, Eariasspp., Eedytolopha aurantium, Elasmopalpus lignosellus, Eldanasaceharina, Ephestia kuehniella, Epinotia spp., Epiphyas postxdttana,Etiella spp., Eulia spp., Eupoetilia ambiguella, Euproctis spp., Euxoaspp., Feltia spp., Galleria mellonella, Graeillaria spp., Grapholithaspp., Hedylepta spp., Helicoverpa spp., Heliothis spp., Hofmannophilapseudospretella, Homoeosoma spp., Homona spp., Hyponomeuta padella,Kakivoria flavofasciata, Laphygma spp., Laspeyresia molesta, Leucinodesorbonalis, Leueoptera spp., Lithicolletis spp., Lithophane antennata,Lobesia spp., Loxagrotis albicosta, Lymantria spp., Lyonetia spp.,Malaeosoma neustria, Maruca testulalis, Klamestra brassieae, Mocis spp.,Myihimna separata, Nymphula spp., Oikelicus spp., Oria spp., Orthagaspp., Ostrinia spp., Oulema oryzae, Panolis flammca, Pamara spp.,Pectinophora spp., Peri leueoptera spp., Phthorimaea spp., Phyllocnistiscitrella, Phyllonorycter spp., Pieris spp., Platynota slultana, Plusiaspp., Plutella xylostella, Prays spp., Prodenia spp., Pratoparce spp.,Pscudaletia spp., Pseudoplusia includens, Pyrausta nubilalis,Rachiplusia nu, Schoenobius spp., Seirpophaga spp., Scotia segetum,Sesamia spp., Sparganothis spp., Spodoptera spp., Stathmopoda spp.,Stomopteryx subsecivella, Synanthedon spp., Tecia solanivora, Thermesiagemmatalis, Tinea pellionella, Tineola bisselliella, Tortrix spp.,Trichoplusia spp., Tula absoluta, Virachola spp.

Examples from the order of the Orthoptera: Achela domeslicus, Blattaorientalis, Blaltella germanica, Dichroplus spp., Gryllotalpa spp.,Leucophaea maderae, Locusta spp., Melanoplus spp., Periplanetaamericana, Schistocerea gregaria.

Examples from the order of Siphonaptera: Ceratophyllus spp., Xenopsyllacheopis.

Example from the order of the Symphyla: Scutigerella spp.

Examples from the order of the Thysanoptera: Anaphothrips obscurus,Baliothrips biformis, Drepanothris reuteri, Enneothrips flavens,Frankliniella spp., Heliolhrips spp., Hercinothrips femoralis,Rhipiphomthrips cruentatus, Scirtothrips spp., Taeniothrips cardamoni,Thrips spp.

Example from the order of the Thysanura: Lepisma saccharina.

Nematodes

All species of plant-parasitic nematodes may in principle be controlledusing the active ingredient combinations of the invention. The activeingredient combinations of the invention prove particularly advantageousin the control of nematodes selected from the group consisting of thefollowing: Aglenchus agricola, Anguina tritici, Aphelenchoidesarachidis, Aphelencboides fragariae, Belonolaimus gracilis, Belonolaimuslongicaudatus, Belonolaimus nortoni, Cacopaurus pestis, Criconemellacurvata, Criconemella onoensis, Criconemella ornata, Criconemellarusiuin, Criconemella xenoplax (=Mesocriconerna xenoplax) andCriconemella spp. in general, Crieonemoides ferniae, Criconemoidesonoense, Criconemoides omatum and Criconemoides spp. in general,Ditylenchus destructor, Dilylenchus dipsaci, Ditylenchus myceliophagusand Ditylenchus spp. in general, Dolichodorus heteroeephalus, Globoderapallida (=Heterodera pallida), Globodera rostochiensis, Globoderasolanacearum, Globodera tabacum, Globodera virginiae, Helicotylenchusdigonicus, Helicolylenchus dihyslera, Helicotylenchus eiythrine,Helicotylenchus multicinctus, Helicotylenchus nannus, Helicotylenchuspseudorobustus and Helicotylenchus spp. in general, Hemicriconemoides,Hemicycliophora arenaria, Hemicycliophora nudata, Heimcycliophoraparvana, Heterodera avenae, Heterodera cruciferae, Heterodera glycines,Heterodera oryzae, Heterodera schachtii, Heterodera zeae and Heteixxleraspp. in general, Hoplolaimus aegyptii, Hoplolaimus califomicus,Hoplolaimus columbus, Hoplolaimus galeiitus, Hoplolaimus indicus,Hoplolaimus inagnistylus, Hoplolannus pararobustus, Longidorusafricanus, Longidorus breviannulalus, Longidorus elongatus, Longidoruslaevicapitatus, Longidorus vineacola and Longidorus spp. in general,Meloidogyne acronea, Meloidogyne africana, Meloidogyne arenaria,Meloidogyne arenaria tharnesi, Meloidogyne artiella, Meloidogynechitwoodi, Meloidogyne coffeicola, Meloidogyne ethiopica, Meloidogyneexigua, Meloidogyne graminicola, Meloidogyne graminis, Meloidogynehapla, Meloidogyne incognita, Meloidogyne incognita acrita, Meloidogynejavanica, Meloidogyne kikuyensis, Meloidogyne naasi, Meloidogyneparanaensis, Meloidogyne thamesi and Meloidogyne spp. in general,Meloinema spp., Nacobbus aberrans, Neotylencbus vigissi, Paraphelenchuspseudopanetinus, Paratrichodorus allius, Paratrichodorus lobatus,Paratrichodorus minor, Paratrichodorus nanus, Paratrichodorus pomsus,Paratrichodorus teres and Paratrichodorus spp. in general, Paratylenchushamalus, Paratylenebus minutus, Paratylenchus projectus andParatylenchus spp. in general, Pratylenchus agilis, Pratylenchus alleni,Pratylenchus andinus, Pratylenchus brachyurus, Pratylenchus cerealis,Pratylenchus coffeae, Pratylenchus crenatus, Pratylenchus delattrei,Pratylenchus giibbicaudatus, Pratylenchus goodeyi, Pratylenchus hamatus,Pratylenchus hexincisus, Pratylenchus loosi, Pratylenchus neglectus,Pratylenchus penetrans, Pratylenchus pralensis, Pratylenchus scribneri,Pratylenchus teres, Pratylenchus thornei, Pratylenchus vulnus,Pratylenchus zeae and Pratylenchus spp. in general, Pseudobalenebusminutus, Psilenchus magmdens, Psilenchus tumidus, Punctodera chalaxnsis,Quinisulcius acutus, Radopholus citrophilus, Radopholus similis,Rolylenchulus borealis, Rotylenchulus parvus, Rotylenchulus renifonnisand Rotylenchulus spp. in general, Rotylenchus laurentinus, Rotylenchusmaemdoratus, Rotylenchus mbustus, Rotylenchus uniformis and Rotylenchusspp. in general, Scutellonema brachyurum, Scutellonema bradys,Scutellonema clathricaudatum and Scutellonema spp. in general,Subanguina radiciola, Tetylenchus nicotianae, Trichodorus eylindncus,Trichodorus minor, Trichodorus primitivus, Trichodorus proximus,Trichodorus similis, Trichodorus sparsus and Trichodorus spp. ingeneral, Tylenchorhynchus agri, Tylenchorhynchus brassicae,Tylenchorhynchus clarus, Tylenchorhynchus claytoni, Tylenchorhynchusdigitatus, Tylenchorhynchus ebriensis, Tylenchorhynchus maximus,Tylenchorhynchus nudus, Tylenchorhynchus vulgaris and Tylenchorhynchusspp. in general, Tylenchulus semipenetrans, Xiphinema americanum,Xiphinema brevicolle, Xiphinema dimorphiamdiitum, Xiphinema index andXiphinema spp. in general.

The active ingredient combinations of the invention prove especiallyadvantageous in the control of nematodes selected from the groupconsisting of the following: Meloidogyne spp., such as Meloidogyneincognita, Meloidogyne javanica, Meloidogyne hapla, Meloidogynearenaria; Ditylenchus ssp., such as Ditylenchus dipsaei, Ditylelenchusdestructor, Pratylenchus ssp., such as Pratylenchus penetrans,Pratylenchus fallax, Pratylenchus coffeae, Pratylenchus loosi,Pratylenchus vulnus; Globodera spp., such as Globodera rostochiensis,Globodera pallida etc.; Heterodera spp., such as Heterodera glycinesHeterodera shachtoii etc.; Aphelenchoides spp., such as Aphelenchoidesbesseyi, Aphelenchoides ritzemabosi, Aphelenchoides fragarieae;Aphelenchus ssp., such as Apbelenchus avenae; Raiktpholus ssp, such asRadopholus similis; Tylenchulus ssp., such as Tylenchulus semipenetrans;Rotylenchulus ssp., such as Rotylenchulus reniformis;

Bursapbelencbus spp., such as Hursaphelencbus xylophilus, Aphelenchoidesspp., Longidorus spp., Xiphinema spp., Trichodorus spp.

Furthermore, the active ingredient combinations of the invention proveactive in the control of nematodes which infect humans or animals, suchas round worm, pin worm, filaria, Wuchereri bancrofti, thread worms(convoluted filaria), Gnathostorna etc.

Animal Health

The active ingredient combinations of the invention do not act onlyagainst plant, hygiene and stored-product pests but also in theveterinary sector, against animal parasites (ecto- and endoparasites)such as hard ticks, soft ticks, mange mites, leaf mites, flies (bitingand licking), parasitic fly larvae, lice, hair lice, feather lice, andfleas. These parasites including the following:

Examples from the order of the Anoplurida: Haematopinus spp.,Linognathus spp., Pediculus spp., Phtirus spp., Solenopotes spp.

Examples from the order of the Mallophagida and the subordersAmblycerina and Ischnocerina: Trimenopon spp., Menopon spp., Trinotonspp., Bovicola spp., Werneckiella spp., Lepikentron spp., Damalina spp.,Trichodectes spp., Felicola spp.

Examples from the order Diptera and the suborders Nematocerina andBrachycerina: Aedes spp., Anopheles spp., Culex spp., Simulium spp.,Eusimulium spp., Phlebotomus spp., Lutzomyia spp., Culicoides spp.,Chrysops spp., Hybomitra spp., Atylotus spp., Tabanus spp., Haematopotaspp., Philipomyia spp., Braula spp., Musca spp., Hydrotaea spp.,Stoinoxys spp., Haematobia spp., Morellia spp., Fannia spp., Glossinaspp., Calliphora spp., Lueilia spp., Cluysomyia spp., Wohlfahrtia spp.,Sarcophaga spp., Oestrus spp., Hypodenna spp., Gasterophilus spp.,Hippobosca spp., Lipoptena spp., Melophagus spp.

Examples from the order of the Siphonapterida: Pulex spp.,Ctenocephalides spp., Xenopsylla spp., Ceratophyllus spp.

Examples from the order of the Heteropterida: Cimex spp., Triatoma spp.,Rhodnius spp., Panstrongylus spp.

Examples from the order of the Blattarida: Blatta orientalis,Periplaneta americana, Blattela germanica, Supella spp.

Examples from the subclass of the Acari (Acarina) and from the orders ofthe Meta- and Mesostigmata: Argas spp., Omithodorus spp., Otobius spp.,Ixodes spp., Amblyomma spp., Boophilus spp., Dermaeentor spp.,Haemophysalis spp., Hyalomma spp., Rhipicephalus spp., Dermanyssus spp.,Raillietia spp., Pneumonyssus spp., Sternostoma spp., Varroa spp.

Examples from the order of the Aetinedida (Prostigmata) and Acaridida(Astigmata): Acarapis spp., Cheyletiella spp., Ormtlioeheyletia spp.,Myobia spp., Psorergates spp., Demodex spp., Trombieula spp.,Listrophorus spp., Acarus spp., Tyrophagus spp., Caloglyphus spp.,Hypodectes spp., Pterolichus spp., Psoroptes spp., Chorioptes spp.,Otodectes spp., Sarcoptes spp., Notoedres spp., Knemidoeoptes spp.,Cytodites spp., Laminosioptes spp.

The active ingredient combinations of the invention are also suitable inthe control of arthropods which infest agricultural livestock, such ascattle, sheep, goats, horses, pigs, donkeys, camels, buffalos, rabbits,chickens, turkeys, ducks, geese and bees, for example, otherdomesticated animals such as dogs, cats, caged birds and aquarium fish,for example, and also so-called experimentation animals, such ashamsters, guinea pigs, rats and mice, for example. The aim ofcontrolling these arthropods is to reduce fatalities and yieldreductions (of meat, milk, wool, hides, eggs, honey, etc.), so that moreeconomic and easier animal husbandry is possible through the use of theactive ingredient combinations of the invention.

Application of the active ingredient combinations of the invention inthe veterinary sector and in animal husbandry is, in a conventional way,through enteral administration in the form of, for example, tablets,capsules, potions, drenches, granules, pastes, boluses, the feed-throughmethod, and suppositories, and by parenteral administration, as forexample through injections (intramuscular, subcutaneous, intravenous,intraperitoneal, etc.), implants, by nasal administration, by dermalapplication in the form, for example, of bathing or dipping, spraying,pour-on and spot-on, washing, and powdering, and also with the aid ofmolded articles containing active ingredient, such as collars, earmarks, tail marks, limb bands, halters, marking devices, etc.

In the context of application for livestock, poultry, domestic animals,etc., the active ingredient combinations may be applied as formulations(for example, powders, emulsions, flowable compositions) which comprisethe active ingredients in an amount from 1 to 80 wt. %, directly orafter 100- to 10 000-fold dilution, or may be used in the form of achemical bath.

Crops

The crops to be protected, which have only been described in a generalmanner, are differentiated and specified below. Thus, with regard touse, vegetables are understood to mean, for example, fruit vegetablesand flower-heads as vegetables, for example carrots, bell peppers,chilli peppers, tomatoes, aubergines, cucumbers, cucurbits, courgettes,broad beans, runner beans, bush beans, peas, artichokes, maize;

but also leafy vegetables, for example lettuce, chicory, endives, cress,rocket salad field salad, iceberg lettuce, leek, spinach, swiss chard;additionally tuber vegetables, root vegetables and stem vegetables, forexample celeriac, beetroot, carrots, garden radish, horseradish,salsify, asparagus, table beet, palm shoots, bamboo shoots, and alsobulb vegetables, for example onions, leek, fennel, garlic;additionally brassica vegetables, such as cauliflower, broccoli,kohlrabi, red cabbage, white cabbage, green cabbage, savoy cabbage,brussels sprouts, Chinese cabbage.

With regard to use, perennial crops are understood to mean citrus fruit,for example oranges, grapefruit, mandarins, lemons, limes, bitteroranges, kumquats, satsumas;

but also pome fruit, for example apples, pears and quince, and stonefruit, for example peaches, nectarines, cherries, plums, common plums,apricots;additionally grapevine, hops, olives, tea, soya, oilseed rape, cotton,sugar cane, beet, potatoes, tobacco and tropical crops, for examplemangoes, papayas, figs, pineapples, dates, bananas, durians, kakis,coconuts, cacao, coffee, avocados, lychees, maracujas, guavas,and also almonds and nuts, for example hazelnuts, walnuts, pistachios,cashew nuts, brazil nuts, pecan nuts, butter nuts, chestnuts, hickorynuts, macadamia nuts, peanuts,and additionally also soft fruit, for example blackcurrants,gooseberries, raspberries, blackberries, blueberries, strawberries, redbilberries, kiwis, cranberries.

With regard to use, ornamental plants are understood to mean annual andperennial plants, for example cut flowers, for example roses,carnations, gerbera, lilies, marguerites, chrysanthemums, tulips,daffodils, anemones, poppies, amaryllis, dahlias, azaleas, malves, butalso, for example, bedding plants, potted plants and shrubs, for exampleroses, tagetes, pansies, geraniums, fuchsias, hibiscus, chrysanthemums,busy lizzies, cyclamen, african violets, sunflowers, begonias, inornamental lawns, in golf lawns, but also in cereals such as barley,wheat, rye, triticale, oats, in rice, in millet, in maize, additionally,for example, bushes and conifers, for example fig trees, rhododendron,spruce trees, fir trees, pine trees, yew trees, juniper trees, stonepines, rose bays.

With regard to use, spices are understood to mean annual and perennialplants, for example aniseed, chilli pepper, bell pepper, pepper,vanilla, majoram, thyme, cloves, juniper berries, cinnamon, tarragon,coriander, saffron, ginger.

The crops to be protected are highlighted in particular as follows: bellpeppers, chilli peppers, tomatoes, aubergines, cucumbers, cucurbits,courgettes, artichokes, maize, celeriac, beetroot, carrots, gardenradish, horseradish, salsifies, asparagus, table beet, palm shoots,bamboo shoots, onions, leek, oranges, grapefruit, mandarins, lemons,limes, bitter oranges, kumquats, satsuinas, apples, pears, and quince,and stone fruit, such as, for example, peaches, nectarines, cherries,plums, common plums, apricots, grapevine, hops, soya, oilseed rape,cotton, sugar cane, beet, potatoes, tobacco, hazelnuts, walnuts,pistachios, cashew nuts, brazil nuts, pecan nuts, butter nuts,chestnuts, hickory nuts, macadamia nuts, peanuts, roses, carnations,gerbera, lilies, marguerites, chrysanthemums, tulips, daffodils,anemones, poppies, amaryllis, dahlias, azaleas, malves, barley, wheat,rye, triticale, oats, nee, millet, maize.

According to the invention, it is possible to treat all plants and plantparts. Plants are understood here to mean all plants and plantpopulations such as desired and undesired wild plants or crop plants(including naturally occurring crop plants). Crop plants may be plantswhich can be obtained by conventional breeding and optimization methodsor by biotechnological and genetic engineering methods or combinationsof these methods, including the transgenic plants and including theplant cultivars which can or cannot be protected by plant breeders'certificates.

GMOs

In a further preferred embodiment, transgenic plants and plant cultivarswhich have been obtained by genetic engineering methods, if appropriatein combination with conventional methods (Genetically ModifiedOrganisms), and parts thereof are treated. The terms “parts” and “plantparts” have been explained above.

More preferably, plants of the plant cultivars which are in each casecommercially available or in use are treated in accordance with theinvention.

Depending on the plant species or plant cultivars, their location andgrowth conditions (soils, climate, vegetation period, nutrition), thetreatment in accordance with the invention may also result insuperadditive (“synergistic”) effects. For example, reduced applicationrates and/or a widening of the activity spectrum and/or an increase inthe activity of the substances and compositions which can be used inaccordance with the invention, better plant growth, increased toleranceto high or low temperatures, increased tolerance to drought or to wateror soil salt content, increased flowering performance, easierharvesting, accelerated maturation, higher harvest yields, betterquality and/or higher nutritional value of the harvested products,better storage qualities and/or processability of the harvested productsare possible which exceed the effects which were actually to beexpected.

According to the invention all plants and plant parts can be treated. Byplants is meant all plants and plant populations such as desirable andundesirable wild plants, cultivars and plant varieties (whether or notprotectable by plant varietal property or plant breeder's rights).Cultivars and plant varieties can be plants obtained by conventionalpropagation and breeding methods which can be assisted or supplementedby one or more biotechnological methods such as by use of doublehaploids, protoplast fusion, random and directed mutagenesis, molecularor genetic markers or by bioengineering anil genetic engineeringmethods. By plant parts are meant all above-ground and below-groundparts and organs of plants such as shoot, leaf, blossom and root, wherefor example leaves, needles, stems, branches, flowers, fruiting bodies,fruits anil seed anil also roots, corms and rhizomes are listed. Cropsanil vegetative anil generative propagating material, for examplecuttings, corns, rhizones, runners anil seals, also belong to plantparts.

Among the plants that can be protected by the method according to theinvention, mention may be made of major field crops such as maize, soyabean, cotton, Brassica oilseeds such as Brassica napus (e.g. canola),Brassica rapa, B. juncea (e.g. mustard) and Brassica carinata, rice,wheat, sugar beet, sugar cane, oats, rye, barley, millet, triticale,flax, vine and various fruits anil vegetables of various botanical taxasuch as Rosaceae sp. (for instance pome fruit such as apples and pears,but also stone fruit such as apricots, cherries, almonds and peaches,soft fruits such as strawberries), Ribesioidae sp., Juglandaceae sp.,Betulaceae sp., Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceaesp., Actinidaceae sp., Lauraceae sp., Musaceae sp. (for instance bananatrees and plantings), Rubiaceae sp. (for instance coffee), Theaeeae sp.,Sterculiceae sp., Rutaceae sp. (for instance lemons, oranges andgrapefruit); Solanaceae sp. (for instance tomatoes, potatoes, peppers,eggplant). Liliaceae sp., Composiliae sp. (for instance lettuce,artichoke and chicory—including root chicory, endive or common chicory),Umbelliferae sp. (for instance carrot, parsley, celery and celeriac),Cucurbitaceae sp. (for instance cucumber—including pickling cucumber,squash, watermelon, gourds and melons), Alliaceae sp. (for instanceonions and leek), Cruciferae sp. (for instance white cabbage, redcabbage, broccoli, cauliflower, brussel sprouts, pak choi, kohlrabi,radish, horseradish, cress, Chinese cabbage), Leguminosae sp. (forinstance peanuts, peas and beans—such as climbing beans and broadbeans). Chenopodiaceae sp. (for instance Swiss chard, while cabbagespinach, beetroots), Malvaceae (for instance okra), Asparagaceae (forinstance asparagus); horticultural and forest crops; ornamental plants;and also genetically modified homologs of these crops.

The method of treatment according to the invention can be used in thetreatment of genetically modified organisms (GMOs), e.g. plants orseals. Genetically modified plants (or transgenic plants) are plants ofwhich a heterologous gene has been stably integrated into the genome.The expression “heterologous gene” essentially means a gene which isprovided or assembled outside the plant and when introduced in thenuclear, chloroplastic or mitochondrial genome gives the transformedplant new or improved agronomic or other properties by expressing aprotein or polypeptide of interest or by downregulating or silencingother gene(s) which are present in the plant (using, for example,antisense technology, cosuppression technology or RNAinterference—RNAi—technology). A heterologous gene that is located inthe genome is also called a transgene. A transgene that is defined byits particular location in the plant genome is called a transformationevent or transgenic event.

Depending on the plant species or plant cultivars, their location andgrowth conditions (sods, climate, vegetation period, nutrition), thetreatment according to the invention may also result in superadditive(“synergistic”) effects. Thus, for example, reduced application ratesand/or a widening of the activity spectrum and/or an increase in theactivity of the active compounds and compositions which can be usedaccording to the invention, better plant growth, increased tolerance tohigh or low temperatures, increased tolerance to drought or to water orsoil salt content, increased flowering performance, easier harvesting,accelerated maturation, higher harvest yields, bigger fruits, largerplant height, greener leaf color, earlier flowering, higher qualityand/or a higher nutritional value of the harvested products, highersugar concentration within the fruits, better storage qualities and/orprocessability of the harvested products are possible, which exceed theeffects which were actually to be expected.

At certain application rates, the active ingredient combinationsaccording to the invention may also have a strengthening effect inplants. Accordingly, they are suitable for mobilizing the defense systemof the plant against attack by unwanted microorganisms. This may, ifappropriate, be one of the reasons of the enhanced activity of thecombinations according to the invention, for example against fungi.Plant-strengthening (resistance-inducing) substances are to beunderstood as meaning, in the present context, also those substances orcombinations of substances which are capable of stimulating the defensesystem of plants in such a way that, when subsequently inoculated withunwanted microorganisms, the treated plants display a substantial degreeof resistance to these microorganisms. In the present case, unwantedmicroorganisms are to be understood as meaning phytopathogenic fungi,bacteria and viruses. Thus, the substances according to the inventioncan be employed for protecting plants against attack by theabovementioned pathogens within a certain period of time after thetreatment. The period of time within which protection is effectedgenerally extends from 1 to 10 days, preferably 1 to 7 days, after thetreatment of the plants with the active ingredients.

Plants and plant cultivars which are preferably treated according to theinvention include all plants which have genetic material which impartsparticularly advantageous, useful trails to these plants (whetherobtained by breeding and/or biotechnological means).

Plants and plant cultivars winch are also preferably treated accordingto the invention are resistant against one or more biotic stresses, i.e.said plants show a better defense against animal and microbial pests,such as against nematodes, insects, mites, phytopathogenic fungi,bacteria, viruses and/or viroids.

For example, examples of nematode-resistant plants are described in U.S.patent application Ser. Nos. 11/765,491, 11/765,494, 10/926,819,10/782,020, 12/032,479, 10/783,417, 10/782,096, 11/657,964, 12/192,904,11/396,808, 12/166,253, 12/166,239, 12/166,124, 12/166,209, 11/762,886,12/364,335, 11/763,947, 12/252,453, 12/209,354, 12/491,396 or12/497,221.

Plants and plant cultivars which may also be treated according to theinvention are those plants which are resistant to one or more abioticstresses. Abiotic stress conditions may include, for example, drought,cold temperature exposure, heat exposure, osmotic stress, flooding,increased soil salinity, increased mineral exposure, ozone exposure,high light exposure, limited availability of nitrogen nutrients, limitedavailability of phosphorus nutrients, or shade avoidance.

Plants and plant cultivars which may also be treated according to theinvention are those plants characterized by enhanced yieldcharacteristics. Increased yield in said plants can be the result of,for example, improved plant physiology, growth and development such aswater use efficiency, water retention efficiency, improved nitrogen use,enhanced carbon assimilation, improved photosynthesis, increasedgermination efficiency and accelerated maturation. Yield can furthermorebe affected by improved plant architecture (under stress and non-stressconditions), including early flowering, flowering control for hybridseed production, seedling vigor, plant size, internode number anddistance, root growth, seed size, fruit size, pod size, pod or earnumber, seed number per pod or ear, seed mass, enhanced seed filling,reduced seed dispersal, reduced pod dehiscence and lodging resistance.Further yield traits include seed composition, such as carbohydratecontent, protein content, oil content and composition, nutritionalvalue, reduction in anti-nutritional compounds, improved processabilityand better storage qualities.

Examples of plants with the above-mentioned traits are non-exhaustivelylisted in table A.

Plants that may be treated according to the invention are hybrid plantsthat already express the characteristics of heterosis or hybrid vigorwhich results in generally higher yield and vigor, and improved healthand resistance toward biotic and abiotic stresses. Such plants aretypically made by crossing an inbred male-sterile parent line (thefemale parent) with another inbred male-fertile parent line (the maleparent). Hybrid seed is typically harvested from the male-sterile plantsand sold to growers. Male-sterile plants can sometimes (e.g. in maize)be produced by detasseling, i.e. the mechanical removal of the malereproductive organs (or male flowers) but, more typically, malesterility is the result of genetic determinants in the plant genome, inthat case, and especially when seeds are the desired product to beharvested from the hybrid plants it is typically useful to ensure thatmale fertility in the hybrid plants is fully restored. This can beaccomplished by ensuring that the male parents have appropriatefertility restorer genes which are capable of restoring the malefertility in hybrid plants that contain the genetic determinantsresponsible for male sterility. Genetic determinants for male sterilitymay be located in the cytoplasm. Examples of cytoplasmic male sterility(CMS) have for example been described in Brassica species (WO 92/05251,WO 95/09910, WO 98/27806, WO 05/002324, WO 06/021972 and U.S. Pat. No.6,229,072). However, genetic determinants for male sterility can also belocated in the nuclear genome. Male-sterile plants can also be obtainedby plant biotechnology methods such as genetic engineering. Aparticularly useful means of obtaining male-sterile plants is describedin WO 89/10396 in which, for example, a ribonuclease such as a barnaseis selectively expressed in the tapetum cells in the stamens. Fertilitycan then be restored by expression in the tapetum cells of aribonuclease inhibitor such as barstar (e.g. WO 91/02069).

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may be treated according to the inventionare herbicide-tolerant plants, i.e. plants made tolerant to one or moregiven herbicides. Such plants can be obtained either by genetictransformation or by selection of plants containing a mutation impartingsuch herbicide tolerance.

Herbicide-resistant plants are for example glyphosate-tolerant plants,i.e. plants made tolerant to the herbicide glyphosate or salts thereof.Plants am be made tolerant to glyphosate through different means. Forexample, glyphosate-tolerant plants can be obtained by transforming theplant with a gene encoding the enzyme 5-enolpyruvylshikimate-3-phosphatesynthase (EPSPS). Examples of such EPSPS genes are the AroA gene (mutantCT7) of the bacterium Salmonella typhimurium (Comai et al., Science(1983), 221, 370-371), the CP4 gene of the bacterium Agrobacterium sp.(Barry et al., Curr. Topics Plant Physiol. (1992), 7, 139-145), thegenes encoding a petunia EPSPS (Shah et al., Science (1986), 233,478-481), a tomato EPSPS (Gasser et al., J. Biol. Chem. (1988), 263,4280-4289), or an eleusine EPSPS (WO 01/66704). It can also be a mutatedEPSPS as described for example in EP 0837944, WO 00/66746, WO 00/66747or WO 02/26995. Glyphosate-tolerant plants can also be obtained byexpressing a gene that encodes a glyphosate oxido-reductase enzyme asdescribed in U.S. Pat. Nos. 5,776,760 and 5,463,175. Glyphosate-tolerantplants am also be obtained by expressing a gene that encodes aglyphosate acetyl transferase enzyme as described in for example WO02/036782, WO 03/092360, WO 05/012515 and WO 07/024782.Glyphosate-tolerant plants can also be obtained by selecting plantscontaining naturally occurring mutations of the above-mentioned genes,as described in for example WO 01/024615 or WO 03/013226. Plantsexpressing EPSPS genes that confer glyphosate tolerance are described ine.g. U.S. patent application Ser. Nos. 11/517,991, 10/739,610,12/139,408, 12/352,532, 11/312,866, 11/315,678, 12/421,292, 11/400,598,11/651,752, 11/681,285, 11/605,824, 12/468,205, 11/760,570, 11/762,526,11/769,327, 11/769,255, 11/943801 or 12/362,774. Plants comprising othergenes that confer glyphosate tolerance, such as decarboxylase genes, aredescribed in e.g. U.S. patent application Ser. Nos. 11/588,811,11/185,342, 12/364,724, 11/185,560 or 12/423,926.

Other herbicide-resistant plants are for example plants that have beenmade tolerant to herbicides inhibiting the enzyme glutamine synthase,such as bialaphos, phosphinothricin or glufosinate. Such plants can beobtained by expressing an enzyme detoxifying the herbicide or a mutantglutamine synthase enzyme that is resistant to inhibition, e.g.described in U.S. patent application Ser. No. 11/760,602. One suchefficient detoxifying enzyme is for example an enzyme encoding aphosphinothricin acetyltransferase (such as the bar or pat protein fromStreptomyces species). Plants expressing an exogenous phosphinothricinacetyltransferase are for example described in U.S. Pat. Nos. 5,561,236;5,648,477; 5,646,024; 5,273,894; 5,637,489; 5,276,268; 5,739,082;5,908,810 and 7,112,665.

Further herbicide-tolerant plants are also plants that have been madetolerant to the herbicides inhibiting the enzymehydroxyphenylpyruvatedioxygenase (HPPD). HPPD is an enzyme thatcatalyses the reaction in which para-hydroxyphenylpyruvate (HPP) istransformed into homogentisate. Plants tolerant to HPPD-inhibitors canbe transformed with a gene encoding a naturally occurring resistant HPPDenzyme, or a gene encoding a mutated or chimeric HPPD enzyme asdescribed in WO 96/38567, WO 99/24585 and WO 99/24586. Tolerance toHPPD-inhibitors can also be obtained by transforming plants with genesencoding certain enzymes enabling the formation of homogentisate despitethe inhibition of the native HPPD enzyme by the HPPD-inhibitor. Suchplants and genes are described in WO 99/34008 and WO 02/36787. Toleranceof plants to HPPD inhibitors can also be improved by transforming plantswith a gene encoding an enzyme having prephenate dehydrogenase (PDH)activity in addition to a gene encoding an HPPD-tolerant enzyme, asdescribed in WO 2004/024928. Further, plants can be made more tolerantto HPPD-inhibitor herbicides by adding into their genome a gene encodingan enzyme capable of metabolizing or degrading HPPD inhibitors, such asthe CYP450 enzymes shown in WO 2007/103567 and WO 2008/150473.

Still further herbicide-resistant plants are plants that have been madetolerant to acetolactate synthase (ALS) inhibitors. Known ALS inhibitorsinclude, for example, sulfonylurea, imidazolinone, triazolopyrimidine,pyrimidinyloxy(thio)benzoate and/or sulfonylaminocarbonyltriazolinoneherbicides. Different mutations in the ALS enzyme (also known asacetohydroxy acid synthase, AHAS) are known to confer tolerance todifferent herbicides and groups of herbicides, as described for examplein Tranel and Wright, Weed Science (2002), 50, 700-712), but also, inU.S. Pat. Nos. 5,605,011, 5,378,824, 5,141,870 and 5,013,659. Theproduction of sulfonylurea-tolerant plants and imidazolinone-tolerantplants is described in U.S. Pat. Nos. 5,605,011; 5,013,659; 5,141,870;5,767,361; 5,731,180; 5,304,732; 4,761,373; 5,331,107; 5,928,937; and5,378,824; and international publication WO 96/33270. Otherimidazolinone-tolerant plants are also described in for example WO2004/040012, WO 2004/106529, WO 2005/020673, WO 2005/093093, WO2006/007373. WO 2006/015376, WO 2006/024351 and WO 2006/060634. Furthersulfonylurea- and imidazolinone-tolerant plants are also described infor example WO 07/024782 and U.S. patent application No. 61/288,958.

Other plants tolerant to imidazolinone and/or sulfonylurea can beobtained by induced mutagenesis, selection in cell cultures in thepresence of the herbicide or mutation breeding as described for examplefor soya beans in U.S. Pat. No. 5,084,082, for rice in WO 97/41218, forsugar beet in U.S. Pat. No. 5,773,702 and WO 99/057965, for lettuce inU.S. Pat. No. 5,198,599 or for sunflower in WO 01/065922.

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may also be treated according to theinvention are insect-resistant transgenic plants, i.e. plants maderesistant to attack by certain target insects. Such plants can beobtained by genetic transformation, or by selection of plants containinga mutation imparting such insect resistance.

An “insect-resistant transgenic plant”, as used herein, includes anyplant containing at least one transgene comprising a coding sequenceencoding:

-   1) an insecticidal crystal protein from Bacillus thuringiensis or an    insecticidal portion thereof, such as the insecticidal crystal    proteins listed by Crickmore et al., Microbiology and Molecular    Biology Reviews (1998), 62, 807-813, updated by Crickmore et    al. (2005) in the Bacillus thuringiensis toxin nomenclature, online    at: http://www.lifesci.sussex.ae.uk/Home/Neil_Criekmore/Bt/), or    insecticidal portions thereof, e.g., proteins of the Cry protein    classes Cry1Ab, Cry1Ac, Cry1B, Cry1C, Cry1D, Cry1F, Cry2Ab, Cry3Aa    or Ciy3Bb or insecticidal portions thereof (e.g. EP-A 1999141 and WO    2007/107302), or such proteins encoded by synthetic genes as for    example described in U.S. patent application Ser. No. 12/249,016; or-   2) a crystal protein from Bacillus thuringiensis or a portion    thereof which is insecticidal in the presence of a second other    crystal protein from Bacillus thuringiensis or a portion thereof,    such as the binary toxin made up of the Cry34 and Cry35 crystal    proteins (Moellenbeck et al., Nat. Biotechnol. (2001), 19, 668-72;    Schnepf et al., Applied Environm. Microbiol. (2006), 71, 1765-1774)    or the binary toxin made up of the Cry1A or Cry 1F proteins and the    Cry2Aa or Cry2Ab or Cry2Ae proteins (U.S. patent application Ser.    No. 12/214,022 and EP 08010791.5); or-   3) a hybrid insecticidal protein comprising parts of two different    insecticidal crystal proteins from Bacillus thuringiensis, such as a    hybrid of the proteins of 1) above or a hybrid of the proteins of 2)    above, e.g. the Cry1A.105 protein produced by arm event MON89034 (WO    2007/027777); or-   4) a protein of any one of 1) to 3) above wherein some, particularly    1 to 10, amino acids have been replaced by another amino acid to    obtain a higher insecticidal activity to a target insect species,    and/or to expand the range of target insect species affected, and/or    because of changes induced in the encoding DNA during cloning or    transformation, such as the Cry3Bb1 protein in arm events MON863 or    MON88017, or the Cry3A protein in corn event MIR604; or-   5) an insecticidal secreted protein Bacillus thuringiensis or from    Bacillus cereus, or an insecticidal portion thereof, such as the    vegetative insecticidal (VIP) proteins listed at:    http://www.lifesci.sussex.ac.uk/home/Neil_Crickmore/Bt/vip.html,    e.g., proteins from the VIP3Aa protein class; or-   6) a secreted protein from Bacillus thuringiensis or Bacillus cereus    which is insecticidal in the presence of a second secreted protein    from Bacillus thuringiensis or B. cereus, such as the binary toxin    made up of the VIP1A and VIP2A proteins (WO 94/21795) or-   7) a hybrid insecticidal protein comprising parts from different    secreted proteins from Bacillus thuringiensis or Bacillus cereus,    such as a hybrid of the proteins in 1) above or a hybrid of the    proteins in 2) above; or-   8) a protein of any one of 5) to 7) above wherein some, particularly    1 to 10, amino acids have been replaced by another amino acid to    obtain a higher insecticidal activity to a target insect species,    and/or to expand the range of target insect species affected, and/or    because of changes introduced into the encoding DNA during cloning    or transformation (while still encoding an insecticidal protein),    such as the VIP3Aa protein in cotton event COT 102; or-   9) a secreted protein from Bacillus thuringiensis or Bacillus cereus    which is insecticidal in the presence of a crystal protein from    Bacillus thuringiensis, such as the binary toxin made up of VIP3 and    Cry1A or Cry1F (U.S. patent application Nos. 61/126,083 and    61/195,019), or the binary toxin made up of the VIP3 protein and the    Cry2Aa or Cry2Ab or Cry2Ae proteins (U.S. patent application Ser.    No. 12/214,022 and EP 08010791.5); or-   10) a protein of 9) above wherein some, particularly 1 to 10, amino    acids have been replaced by another amino acid to obtain a higher    insecticidal activity to a target insect species, and/or to expand    the range of target insect species affected, and/or because of    changes introduced into the encoding DNA during cloning or    transformation (while still encoding an insecticidal protein).

Of course, an insect-resistant transgenic plant, as used herein, alsoincludes any plant comprising a combination of genes encoding theproteins of any one of the above classes 1 to 10. In one embodiment, aninsect-resistant plant contains more than one transgene encoding aprotein of any one of the above classes 1 to 10, to expand the range oftarget insect species affected when using different proteins directed atdifferent target insect species, or to delay insect resistancedevelopment to the plants by using different proteins insecticidal tothe same target insect species but having a different mode of action,such as binding to different receptor binding sites in the insect.

An “insect-resistant transgenic plant”, as used herein, further includesany plant containing at least one transgene comprising a sequenceproducing upon expression a double-stranded RNA which upon ingestion bya plant insect pest inhibits the growth of this insect pest, asdescribed for example in WO 2007/080126, WO 2006/129204, WO 2007/074405,WO 2007/080127 and WO 2007/035650.

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may also be treated according to theinvention are tolerant to abiotic stresses. Such plants can be obtainedby genetic transformation, or by selection of plants containing amutation imparting such stress resistance. Particularly useful stresstolerance plants include:

-   1) plants which contain a transgene capable of reducing the    expression and/or the activity of the poly(ADP-ribose)polymerase    (PARP) gene in the plant cells or plants as described in WO    00/04173, WO/2006/045633, EP 04077984.5 or EP 06009836.5;-   2) plants which contain a stress tolerance-enhancing transgene    capable of reducing the expression and/or the activity of the    PARG-encoding genes of the plants or plants cells, as described in    e.g. WO 2004/090140;-   3) plants which contain a stress tolerance-enhancing transgene    encoding a plant-functional enzyme of the nicotinamide adenine    dinucleotide salvage biosynthesis pathway including nicotinamidase,    nicotinate phosphoribosyltransferase, nicotinic acid mononucleotide    adenyl transferase, nicotinamide adenine dinucleotide synthetase or    nicotine amide phosphoribosyltransferase as described e.g. in EP    04077624.7, WO 2006/133827, PCT/EP07/002433, EP 1999263 or WO    2007/107326.

Plants or plant cultivars (obtained by plant biotechnology methods suchas genetic engineering) which may also be treated according (o theinvention show altered quantity, quality and/or storage qualities of theharvested product and/or altered properties of specific constituents ofthe harvested product, such as:

-   1) transgene plants which synthesize a modified starch, which in its    physical-chemical characteristics, in particular the amylose content    or the amylose/amylopectin ratio, the degree of branching, the    average chain length, the side chain distribution, the viscosity    behavior, the gelling strength, the starch grain size and/or the    starch grain morphology, is changed in comparison with the    synthesized starch in wild type plant cells or plants, so that this    modified starch is better suited for special applications. Such    transgenic plants synthesizing a modified starch are disclosed, for    example in EP 0571427, WO 95/04826, EP 0719338, WO 96/15248, WO    96/19581, WO 96/27674, WO 97/11188, WO 97/26362, WO 97/32985, WO    97/42328, WO 97/44472, WO 97/45545, WO 98/27212, WO 98/40503, WO    99/58688, WO 99/58690, WO 99/58654, WO 00/08184, WO 00/08185, WO    00/08175, WO 00/28052, WO 00/77229, WO 01/12782, WO 01/12826, WO    02/101059, WO03/071860, WO 2004/056999, WO 2005/030942, WO    2005/030941, WO 2005/095632, WO 2005/095617, WO 2005/095619, WO    2005/095618, WO 2005/123927, WO 2006/018319, WO 2006/103107, WO    2006/108702, WO 2007/009823, WO 00/22140, WO 2006/063862, WO    2006/072603, WO 02/034923, EP 06090134.5, EP 06090228.5, EP    06090227.7, EP 0709007.1, EP 07090009.7, WO 01/14569, WO 02/79410,    WO 03/33540, WO 2004/078983, WO 01/19975, WO 95/26407, WO 96/34968,    WO 98/20145, WO 99/12950, WO 99/66150, WO 99/53072, U.S. Pat. No.    6,734,341, WO 00/11192, WO 98/22604, WO 98/32326, WO 01/98509, WO    01/98509, WO 2005/002359, U.S. Pat. Nos. 5,824,790, 6,013,861, WO    94/04693, WO 94/09144, WO 94/11520, WO 95/35026 and WO 97/20936.-   2) Transgenic plants which synthesize non-starch carbohydrate    polymers or which synthesize non-starch carbohydrate polymers with    altered properties in comparison to wild type plants without genetic    modification. Example are plants producing polyfructose, especially    of the inulin and levan type, as disclosed in EP 0663956, WO    96/01904, WO 96/21023, WO 98/39460 and WO 99/24593, plants producing    alpha-1,4-glucans as disclosed in WO 95/31553, US 2002031826, U.S.    Pat. Nos. 6,284,479, 5,712,107, WO 97/47806, WO 97/47807, WO    97/47808 and WO 00/14249, plants producing alpha-1,6 branched    alpha-1,4-glucans, as disclosed in WO 00/73422, and plants producing    alternan, as disclosed in WO 00/47727, WO 00/73422, EP 06077301.7,    U.S. Pat. No. 5,908,975 and EP 0728213.-   3) Transgenic plants which produce hyaluronan, as for example    disclosed in WO 2006/032538, WO 2007/039314, WO 2007/039315, WO    2007/039316, JP 2006304779 and WO 2005/012529.-   4) Transgenic plants or hybrid plants, such as onions with    characteristics such as ‘high soluble solids content’, ‘low    pungency’ (LP) and/or ‘long storage’ (LS), as described in U.S.    patent application Ser. Nos. 12/020,360 and 61/054,026.

Plants or plant cultivars (that have been obtained by plantbiotechnology methods such as genetic engineering) which may also betreated according to the invention are plants, such as cotton plants,with altered fiber characteristics. Such plants can be obtained bygenetic transformation, or by selection of plants which contain amutation imparting such altered fiber characteristics and include:

-   a) plants, such as cotton plants, containing an altered form of    cellulose synthase genes as described in WO 98/00549,-   b) plants, such as cotton plants, containing an altered form of rsw2    or rsw3 homologous nucleic acids as described in WO 2004/053219;-   c) plants, such as cotton plants, with increased expression of    sucrose phosphate synthase as described in WO 01/17333;-   d) plants, such as cotton plants, with increased expression of    sucrose synthase as described in WO 02/45485;-   e) plants, such as cotton plants, wherein the timing of the    plasmodesmatal gating at the basis of the fiber cell is altered,    e.g. through downregulation of fiber-selective β-1,3-glucanase as    described in WO 2005/017157, or as described in EP 08075514.3 or in    U.S. patent application No. 61/128,938;-   f) plants, such as cotton plants, having fibers with altered    reactivity, e.g. through the expression of    N-acetylglucosamintransferase gene including nodC and chitin    synthase genes as described in WO 2006/136351.

Plants or plant cultivars (that have been obtained by plantbiotechnology methods such as genetic engineering) which may also betreated according to the invention are plants, such as oilseed rape orrelated Brassica plants, with altered oil profile characteristics. Suchplants can be obtained by genetic transformation, or by selection ofplants which contain a mutation imparting such altered oilcharacteristics and include:

-   a) plants, such as oilseed rape plants, producing oil having a high    oleic acid content as described e.g. in U.S. Pat. Nos. 5,969,169,    5,840,946 or 6,323,392 or 6,063,947;-   b) plants such as oilseed rape plants, producing oil having a low    linolenic acid content as described in U.S. Pat. Nos. 6,270,828,    6,169,190 or 5,965,755.-   c) Plants such as oilseed rape plants, producing oil having a low    level of saturated fatty acids as described e.g. in U.S. Pat. No.    5,434,283 or U.S. patent application Ser. No. 12/668,303.

Plants or plant cultivars (that have been obtained by plantbiotechnology methods such as genetic engineering) which may also betreated according to the invention are plants, such as oilseed rape orrelated Brassica plants, with altered seed shattering characteristics.Such plants can be obtained by genetic transformation, or by selectionof plants which contain a mutation imparting such altered seedshattering characteristics and include plants such as oilseed rapeplants with delayed or reduced seed shattering as described in U.S.patent application No. 61/135,230, WO09/068313 and WO10/006732.

Particularly useful transgenic plants which may be treated according tothe invention are plants containing transformation events, orcombinations of transformation events, that are the subject of petitionsfor non-regulated status, in the United States of America, to the Animaland Plant Health Inspection Service (APHIS) of the United StatesDepartment of Agriculture (USDA), whether such petitions are granted orare still pending. At any lime this information is readily availablefrom APHIS (4700 River Road, Riverdale, Md. 20737, USA), for instance onits internet site (URL http://www.aphis.usda.gov/brs/not_reg.html). Onthe filing date of this application the petitions for non-regulatedstatus that were pending with APHIS or granted by APHIS were thoselisted in table B which contains the following information:

-   -   Petition: the identification number of the petition. Technical        descriptions of the transformation events can be found in the        individual petition documents which are obtainable from APHIS,        for example on the APHIS website, by reference to this petition        number. These descriptions are herein incorporated by reference.    -   Extension of a petition: reference to a previous petition for        which an extension is requested.    -   Institution: the name of the entity submitting the petition.    -   Regulated article: the plant species concerned.    -   Transgenic phenotype: the trait conferred to the plants by the        transformation event.    -   Transformation event or line: the name of the event or events        (sometimes also designated as line or lines) for which        non-regulated status is requested.    -   APHIS documents: various documents published by APHIS in        relation to the petition and which can be requested from APHIS.

Additionally particularly useful plants containing single transformationevents or a combination of transformation events are listed for examplein the database from various national or regional regulatory agencies(see for example http://gmoinfo.jrc.it/gmp_browse.aspx andhttp://cera-gmc.org/index.php?evidcode=&hstIDXCode=&gType=&AbbrCode=&atCode-&stCode=&coIDCode=&action=gm_crop_database&mode=Submit).

Further particular transgenic plants include plants containing atransgene in an agronomically neutral or beneficial position asdescribed in any of the patent publications listed in table C.

In one embodiment of the invention the plants A-1 to A-183 of table A,in total or in part, or propagation material of said plants, is treatedor contacted with the active ingredient combinations of the invention,alone or in the form of compositions comprising an active ingredientcombination.

Transgenic No. event Company Description Crop A-1 ASR368 Scotts SeedsGlyphosate tolerance derived by inserting a modified 5- Agrostisenolpyruvylshikimate-3-phosphate synthase (EPSPS) stolonifera encodinggene from Agrobacterium tumefaciens, parent Creeping line B99061.bentgrass A-2 Asr-368 Glyphosate tolerance; US 2006-162007 bentgrass A-3H7-1 Monsanto Glyphosate herbicide tolerant sugar beet produced by Betavulgaris Company inserting a gene encoding the enzyme 5-enolypyruvylshikimate-3-phosphate synthase (EPSPS) from the CP4 strainof Agrobacterium tumefaciens; WO 2004-074492 A-4 T120-7 Bayer Crop-Introduction of the PPT-acetyltransferase (PAT) Beta vulgaris Scienceencoding gene from Streptomyces viridochromogenes, (Aventis Crop- anaerobic soil bacterium. PPT normally acts to inhibit Science glutaminesynthetase, causing a fatal accumulation of (AgrEvo)) ammonia.Acetylated PPT is inactive. A-5 GTSB77 Novartis Seeds; Glyphosateherbicide tolerant sugar beet produced by Beta vulgaris Monsantoinserting a gene encoding the enzyme 5- (sugar beet) Companyenolypyruvylshikimate-3-phosphate synthase (EPSPS) from the CP4 strainof Agrobacterium tumefaciens. A-6 T227-1 Glyphosate tolerance; US2004-117870 Beta vulgaris sugar beet A-7 23-18-17, 23- Monsanto Highlaurate acid (12:0) and myristate acid (14:0) canola Brassica 198Company produced by inserting a thioesterase encoding gene from napus(formerly the California bay laurel (Umbellularia californica).(Argentine Calgene) Canola) A-8 45A37, 46A40 Pioneer Hi-Bred High oleicacid and low linolenic acid canola produced Brassica Internationalthrough a combination of chemical mutagenesis to select napus Inc. for afatty acid desaturase mutant with elevated oleic (Argentine acidcontent, and traditional back-crossing to introduce Canola) the lowlinolenic acid trait. A-9 46A12, 46A16 Pioneer Hi-Bred Combination ofchemical mutagenesis, to achieve the Brassica International high oleicacid trait, and traditional breeding with napus Inc. registered canolavarieties. (Argentine Canola) A-10 GT200 Monsanto Glyphosate herbicidetolerant canola produced by Brassica Company inserting genes encodingthe enzymes 5- napus enolypyruvylshikimate-3-phosphate synthase (EPSPS)(Argentine from the CP4 strain of Agrobacterium tumefaciens and Canola)glyphosate oxidase from Ochrobactrum anthropi. A-11 GT73, RT73 MonsantoGlyphosate herbicide tolerant canola produced by Brassica Companyinserting genes encoding the enzymes 5- napusenolypyruvylshikimate-3-phosphate synthase (EPSPS) (Argentine from theCP4 strain of Agrobacterium tumefaciens and Canola) glyphosate oxidasefrom Ochrobactrum anthropi. A-12 HCN10 Aventis Introduction of thePPT-acetyltransferase (PAT) Brassica CropScience encoding gene fromStreptomyces viridochromogenes, napus an aerobic soil bacterium. PPTnormally acts to inhibit (Argentine glutamine synthetase, causing afatal accumulation of Canola) ammonia. Acetylated PPT is inactive. A-13HCN92 Bayer Crop- Introduction of the PPT-acetyltransferase (PAT)Brassica Science encoding gene from Streptomyces viridochromogenes,napus (Aventis Crop- an aerobic soil bacterium. PPT normally acts toinhibit (Argentine Science glutamine synthetase, causing a fatalaccumulation of Canola) (AgrEvo)) ammonia. Acetylated PPT is inactive.A-14 MS1, RF1 => Aventis Male sterility, fertility restoration,pollination control Brassica PGS1 CropScience system displayingglufosinate herbicide tolerance. MS napus (formerly Plant linescontained the barnase gene from Bacillus (Argentine Geneticamyloliquefaciens, RF lines contained the barstar gene Canola) Systems)from the same bacterium, and both lines contained the phosphinothricinN-acetyltransferase (PAT) encoding gene from Streptomyces hygroscopicus.A-15 MS1, RF2 => Aventis Male sterility, fertility restoration,pollination control Brassica PGS2 CropScience system displayingglufosinate herbicide tolerance. MS napus (formerly Plant linescontained the barnase gene from Bacillus (Argentine Geneticamyloliquefaciens, RF lines contained the barstar gene Canola) Systems)from the same bacterium, and both lines contained the phosphinothricinN-acetyltransferase (PAT) encoding gene from Streptomyces hygroscopicus.A-16 MS8 × RF3 Bayer Male sterility, fertility restoration, pollinationcontrol Brassica CropScience system displaying glufosinate herbicidetolerance. MS napus (Aventis lines contained the barnase gene fromBacillus (Argentine CropScience amyloliquefaciens, RF lines containedthe barstar gene Canola) (AgrEvo)) from the same bacterium, and bothlines contained the phosphinothricin N-acetyltransferase (PAT) encodinggene from Streptomyces hygroscopicus. A-17 MS-B2 Male sterility, WO01/31042 Brassica napus (Argentine Canola) A-18 MS-BN1/RF- Malesterility/restoration; WO 01/41558 Brassica BN1 napus (Argentine Canola)A-19 NS738, Pioneer Hi-Bred Selection of somaclonal variants withaltered Brassica NS1471, International acetolactate synthase (ALS)enzymes, following napus NS1473 Inc. chemical mutagenesis. Two lines(P1, P2) were initially (Argentine selected with modifications atdifferent unlinked loci. Canola) NS738 contains the P2 mutation only.A-20 OXY-235 Aventis Tolerance to the herbicides bromoxynil and ioxynilby Brassica CropScience incorporation of the nitrilase gene fromKlebsiella napus (formerly Rhône pneumoniae. (Argentine Poulenc Inc.)Canola) A-21 PHY14, Aventis Male sterility was obtained via insertion ofthe barnase Brassica PHY35 CropScience ribonuclease gene from Bacillusamyloliquefaciens; napus (formerly Plant fertility restoration byinsertion of the barstar RNase (Argentine Genetic inhibitor; PPTresistance via PPT-acetyltransferase Canola) Systems) (PAT) fromStreptomyces hygroscopicus. A-22 PHY36 Aventis Male sterility wasobtained via insertion of the barnase Brassica CropScience ribonucleasegene from Bacillus amyloliquefaciens; napus (formerly Plant fertilityrestoration by insertion of the barstar RNase (Argentine Geneticinhibitor; PPT-acetyltransferase (PAT) from Canola) Systems)Streptomyces hygroscopicus. A-23 RT73 Glyphosate resistance; WO 02/36831Brassica napus (Argentine Canola) A-24 T45 (HCN28) Bayer Crop-Introduction of the PPT-acetyltransferase (PAT) Brassica Scienceencoding gene from Streptomyces viridochromogenes, napus (Aventis anaerobic soil bacterium. PPT normally acts to inhibit (ArgentineCropScience glutamine synthetase, causing a fatal accumulation ofCanola) (AgrEvo)) ammonia. Acetylated PPT is inactive. A-25 HCR-1 BayerCrop Introduction of the glufosinate ammonium herbicide Brassica Sciencetolerance trait from transgenic B. napus line T45. This rapa (Aventistrait is imparted by the gene for phosphinothricin (Polish CropScienceacetyltransferase (PAT) from S. viridochromogenes. Canola) (AgrEvo))A-26 ZSR500/502 Monsanto Introduction of a modified5-enol-pyruvylshikimate-3- Brassica Company phosphate synthase (EPSPS)and a gene from rapa Achromobacter sp., that degrades glyphosate by(Polish conversion to aminomethylphosphonic acid (AMPA) Canola) andglyoxylate by interspecific crossing with GT73. A-27 EE-1 Insectresistance (Cry1Ac); WO 2007/091277 aubergine A-28 55-1/63-1 CornellPapaya ringspot virus (PRSV)-resistant papaya produced Carica Universityby inserting the coat protein (CP)-encoding sequences papaya from thisplant potyvirus. (papaya) A-29 RM3-3, RM3- Bejo Zaden BV Male sterilitywas obtained via insertion of the barnase Cichorium 4, RMS-6ribonuclease gene from Bacillus amyloliquefaciens; PPT intybusresistance was obtained via the bar gene from (chicory) S.hygroscopicus, which encodes the PAT enzyme. A-30 A, B Agritope Inc.Reduced accumulation of S-adenosylmethionine (SAM), Cucumis andconsequently reduced ethylene synthesis, by melo introduction of thegene encoding S-adenosylmethionine (melon) hydrolase. A-31 CZW-3 Asgrow(USA); Cucumber mosaic virus (CMV)-, zucchini yellows Cucurbita Seminismosaic virus (ZYMV)- and watermelon mosaic virus pepo Vegetable Inc.(WMV) 2-resistant squash (Curcurbita pepo) produced (squash) (Canada) byinserting the coat protein (CP)-encoding sequences from each of theseplant viruses into the host genome. A-32 ZW20 Upjohn (USA); Zucchiniyellows mosaic (ZYMV)- and watermelon Cucurbita Seminis mosaic virus(WMV) 2-resistant squash (Curcurbita pepo Vegetable Inc. pepo) producedby inserting the coat protein (squash) (Canada) (CP)-encoding sequencesfrom each of these plant potyviruses into the host genome. A-33 66Florigene Pty Delayed senescence and sulfonylurea herbicide-tolerantDianthus Ltd. carnations produced by inserting a truncated copy of thecaryophyllus carnation aminocyclopropane cyclase (ACC) synthase(carnation) encoding gene in order to suppress expression of theendogenous unmodified gene, which is required for normal ethylenebiosynthesis. Tolerance to sulfonylurea herbicides was obtained via theintroduction of a chlorosulfuron-tolerant version of the acetolactatesynthase (ALS)-encoding gene from tobacco. A-34 4, 11, 15, 16 FlorigenePty Modified color and sulfonylurea herbicide-tolerant Dianthus Ltd.carnations produced by inserting two anthocyanin caryophyllusbiosynthetic genes whose expression results in a (carnation)violet/mauve coloration. Tolerance to sulfonylurea herbicides wasobtained via the introduction of a chlorosulfuron-tolerant version ofthe acetolactate synthase (ALS)-encoding gene from tobacco. A-35 959A,988A, Florigene Pty Introduction of two anthocyanin biosynthetic genesDianthus 1226A, 1351A, Ltd. which results in a violet/mauve coloration;introduction caryophyllus 1363A, 1400A of a variant form of acetolactatesynthase (ALS). (carnation) A-36 3560.4.3.5 Glyphosate/ALSinhibitor-tolerance; WO 2008002872 Glycine max L. (soya bean) A-37A2704-12 Glufosinate tolerance; WO 2006/108674 Glycine max L. (soyabean) A-38 A2704-12, Aventis Glufosinate ammonium herbicide-tolerantsoya bean Glycine max A2704-21, CropScience produced by inserting amodified phosphinothricin L. (soya A5547-35 acetyltransferase(PAT)-encoding gene from the soil bean) bacterium Streptomycesviridochromogenes. A-39 A5547-127 Bayer Glufosinate ammoniumherbicide-tolerant soya bean Glycine max CropScience produced byinserting a modified phosphinothricin L. (soya (Aventisacetyltransferase (PAT)-encoding gene from the soil bean) CropSciencebacterium Streptomyces viridochromogenes. (AgrEvo)) A-40 A5547-35Glufosinate tolerance; WO 2006/108675 Glycine max L. (soya bean) A-41DP-305423-1 High oleic acid content/ALS inhibitor tolerance; Glycine maxWO 2008/054747 L. (soya bean) A-42 DP356043 Pioneer Hi-Bred Soya beanevent with two herbicide tolerance genes: Glycine max Internationalglyphosate N-acetyltransferase, which detoxifies L. (soya Inc.glyphosate, and a modified acetolactate synthase (A bean) A-43 G94-1,G94- DuPont Canada High oleic acid soya bean produced by inserting aGlycine max 19, G168 Agricultural second copy of the fatty aciddesaturase (GmFad2-1) L. (soya Products encoding gene from soya bean,which resulted in bean) “silencing” of the endogenous host gene. A-44GTS 40-3-2 Monsanto Glyphosate-tolerant soya bean variety produced byGlycine max Company inserting a modified 5-enolpyruvylshikimate-3- L.(soya phosphate synthase (EPSPS)-encoding gene from the bean) soilbacterium Agrobacterium tumefaciens. A-45 GU262 Bayer Glufosinateammonium herbicide-tolerant soya bean Glycine max CropScience producedby inserting a modified phosphinothricin L. (soya (Aventisacetyltransferase (PAT)-encoding gene from the soil bean) CropSciencebacterium Streptomyces viridochromogenes. (AgrEvo)) A-46 MON87701 Insectresistance (Cry1Ac); WO 2009064652 Glycine max L. (soya bean) A-47MON87705 altered fatty acid levels (mid-oleic acid and low Glycine maxsaturated); WO 2010037016 L. (soya bean) A-48 MON87754 Increased oilcontent; WO 2010024976 Glycine max L. (soya bean) A-49 MON87769Stearidonic acid (SDA)-comprising oil; Glycine max WO 2009102873 L.(soya bean) A-50 MON89788 Monsanto Glyphosate-tolerant soya bean varietyproduced by Glycine max Company inserting a modified5-enolpyruvylshikimate-3- L. (soya phosphate synthase (EPSPS)-encodingaroA (epsps) bean) gene from Agrobacterium tumefaciens CP4; WO2006130436 A-51 OT96-15 Agriculture & Low linolenic acid soya beanproduced through Glycine max Agri-Food traditional cross-breeding toincorporate the novel trait L. (soya Canada from a naturally occurringfan1 gene mutant that was bean) selected for low linolenic acid content.A-52 W62, W98 Bayer Glufosinate ammonium herbicide-tolerant soya beanGlycine max CropScience produced by inserting a modifiedphosphinothricin L. (soya (Aventis acetyltransferase (PAT)-encoding genefrom the soil bean) CropScience bacterium Streptomyces hygroscopicus.(AgrEvo)) A-53 15985 Monsanto Insect-resistant cotton derived bytransformation of the Gossypium Company DP50B parent variety, whichcontained event 531 hirsutum L. (expressing Cry1Ac protein), withpurified plasmid (cotton) DNA containing the cry2Ab- gene from B.thuringiensis subsp. kurstaki. A-54 1143-14A Insect resistance (Cry1Ab);WO 2006/128569 Gossypium hirsutum L. (cotton) A-55 1143-51B Insectresistance (Cry1Ab); WO 2006/128570 Gossypium hirsutum L. (cotton) A-5619-51A DuPont Canada Introduction of a variant form of acetolactatesynthase Gossypium Agricultural (ALS). hirsutum L. Products (cotton)A-57 281-24-236 DOW Insect-resistant cotton produced by inserting thecry1F Gossypium AgroSciences gene from Bacillus thuringiensisvar.aizawai. The hirsutum L. LLC PAT-encoding gene from Streptomyces(cotton) viridochromogenes was introduced as a selectable marker. A-583006-210-23 DOW Insect-resistant cotton produced by inserting the cry1AcGossypium AgroSciences gene from Bacillus thuringiensissubsp. kurstaki.The hirsutum L. LLC PAT-encoding gene from Streptomyces (cotton)viridochromogenes was introduced as a selectable marker. A-5931807/31808 Calgene Inc. Insect-resistant bromoxynil herbicide-tolerantcotton Gossypium produced by inserting the cry1Ac gene from Bacillushirsutum L. thuringiensis and a nitrilase-encoding gene from (cotton)Klebsiella pneumoniae. A-60 BXN Calgene Inc. Bromoxynilherbicide-tolerant cotton produced by Gossypium inserting anitrilase-encoding gene from Klebsiella hirsutum L. pneumoniae. (cotton)A-61 CE43-67B Insect resistance (Cry1Ab); WO 2006/128573 Gossypiumhirsutum L. (cotton) A-62 CE44-69D Insect resistance (Cry1Ab); WO2006/128571 Gossypium hirsutum L. (cotton) A-63 CE46-02A Insectresistance (Cry1Ab); WO 2006/128572 Gossypium hirsutum L. (cotton) A-64Cot102 Insect resistance (Vip3A); US 2006-130175 Gossypium hirsutum L.(cotton) A-65 COT102 Syngenta Seeds, Insect-resistant cotton produced byinserting the Gossypium Inc. vip3A(a) gene from Bacillus thuringiensisAB88. The hirsutum L. APH4-encoding gene from E. coli was introduced asa (cotton) selectable marker. A-66 COT202 Insect resistance (VIP3A);US2009181399 Gossypium hirsutum L. (cotton) A-67 Cot202 Insectresistance (VIP3); US 2007-067868 Gossypium hirsutum L. (cotton) A-68DAS-21Ø23-5 × DOW WideStrike ™, a stacked insect-resistant cottonderived Gossypium DAS-24236-5 AgroSciences from conventionalcross-breeding of parental lines 3006- hirsutum L. LLC 210-23 (OECDidentifier: DAS-21Ø23-5) and 281-24- (cotton) 236 (OECD identifier:DAS-24236-5). A-69 DAS-21Ø23-5 × DOW Stacked insect-resistant andglyphosate-tolerant cotton Gossypium DAS-24236-5 × AgroSciences derivedfrom conventional cross-breeding of WideStrike hirsutum L. MON88913 LLCund cotton (OECD identifier: DAS-21Ø23-5 × DAS-24236- (cotton) PioneerHi-Bred 5) with MON88913, known as RoundupReady Flex International (OECDidentifier: MON-88913-8). Inc. A-70 DAS-21Ø23-5 × DOWWideStrike ™/Roundup Ready ® cotton, a stacked Gossypium DAS-24236-5 ×AgroSciences insect-resistant and glyphosate-tolerant cotton derivedhirsutum L. MON-Ø1445-2 LLC from conventional cross-breeding ofWideStrike cotton (cotton) (OECD identifier: DAS-21Ø23-5 × DAS-24236-5)with MON1445 (OECD identifier: MON-Ø1445-2). A-71 EE-GH3 Glyphosatetolerance; WO 2007/017186 Gossypium hirsutum L. (cotton) A-72 EE-GH5Insect resistance (Cry1Ab); WO 2008/122406 Gossypium hirsutum L.(cotton) A-73 EE-GH6 Insect resistance (cry2Ae); WO2008151780 Gossypiumhirsutum L. (cotton) A-74 event 281-24- Insect resistance (Cry1F); WO2005/103266 Gossypium 236 hirsutum L. (cotton) A-75 event3006- Insectresistance (Cry1Ac); WO 2005/103266 Gossypium 210-23 hirsutum L.(cotton) A-76 GBH614 Bayer Glyphosate herbicide-tolerant cotton producedby Gossypium CropScience inserting the 2MEPSPS gene into varietyCoker312 by hirsutum L. (Aventis Agrobacterium under the control ofPh4a748At and (cotton) CropScience TpotpC. (AgrEvo)) A-77 LLCotton25Bayer Glufosinate ammonium herbicide-tolerant cotton GossypiumCropScience produced by inserting a modified phosphinothricin hirsutumL. (Aventis acetyltransferase (PAT)-encoding gene from the soil (cotton)CropScience bacterium Streptomyces hygroscopicus; (AgrEvo)) WO2003013224 A-78 LLCotton25 × Bayer Stacked herbicide-tolerant andinsect-resistant cotton Gossypium MON15985 CropScience combiningtolerance to glufosinate ammonium herbicide hirsutum L. (Aventis fromLLCotton25 (OECD identifier: ACS-GHØØ1-3) (cotton) CropScience withresistance to insects from MON15985 (OECD (AgrEvo)) identifier:MON-15985-7). A-79 MON 15985 Insect resistance (Cry1A/Cry2Ab); US2004-250317 Gossypium hirsutum L. (cotton) A-80 MON1445/1698 MonsantoGlyphosate herbicide-tolerant cotton produced by Gossypium Companyinserting a naturally glyphosate-tolerant form of the hirsutum L. enzyme5-enolpyruvylshikimate-3-phosphate synthase (cotton) (EPSPS) from theCP4 strain of A. tumefaciens. A-81 MON15985 × Monsanto Stackedinsect-resistant and glyphosate-tolerant cotton Gossypium MON88913Company produced by conventional cross-breeding of the parental hirsutumL. lines MON88913 (OECD identifier: MON-88913-8) and (cotton) 15985(OECD identifier: MON-15985-7). Glyphosate tolerance is derived fromline MON88913 which contains two genes encoding the enzyme 5-enolypyruvylshikimate-3-phosphate synthase (EPSPS) from the CP4 strainof Agrobacterium tumefaciens. Insect resistance is derived from the lineMON15985 which was produced by transformation of the DP50B parentvariety, which contained event 531 (expressing the Cry1Ac protein), withpurified plasmid DNA containing the cry2Ab gene from B. thuringiensissubsp. kurstaki. A-82 MON-15985-7 × Monsanto Stacked insect-resistantand herbicide-tolerant cotton Gossypium MON-Ø1445-2 Company derived fromconventional cross-breeding of the parental hirsutum L. lines 15985(OECD identifier: MON-15985-7) and (cotton) MON-1445 (OECD identifier:MON-Ø1445-2). A-83 MON531/757/ Monsanto Insect-resistant cotton producedby inserting the cry1Ac Gossypium 1076 Company gene from Bacillusthuringiensis subsp. kurstaki HD-73 hirsutum L. (B.t.k.). (cotton) A-84MON88913 Monsanto Glyphosate herbicide-tolerant cotton produced byGossypium Company inserting two genes encoding the enzyme 5- hirsutum L.enolypyruvylshikimate-3-phosphate synthase (EPSPS) (cotton) from the CP4strain of Agrobacterium tumefaciens; WO 2004/072235 A-85 MON-ØØ531-Monsanto Stacked insect-resistant and herbicide-tolerant cottonGossypium 6 × MON- Company derived from conventional cross-breeding ofthe parental hirsutum L. Ø1445-2 lines MON531 (OECD identifier:MON-ØØ531-6) and (cotton) MON-1445 (OECD identifier: MON-Ø1445-2). A-86PV-GHGT07 Glyphosate tolerance; US 2004-148666 Gossypium (1445) hirsutumL. (cotton) A-87 T304-40 Insect resistance (Cry1Ab); WO2008/122406Gossypium hirsutum L. (cotton) A-88 T342-142 Insect resistance (Cry1Ab);WO 2006/128568 Gossypium hirsutum L. (cotton) A-89 X81359 BASF Inc.Tolerance to imidazolinone herbicides by selection of a Helianthusnaturally occurring mutant. annuus (sunflower) A-90 RH44 BASF Inc.Selection for a mutagenized version of the enzyme Lens acetohydroxy acidsynthase (AHAS), also known as culinaris acetolactate synthase (ALS) oracetolactate pyruvate (lentil) lyase. A-91 FP967 University of A variantform of acetolactate synthase (ALS) was Linum Saskatchewan, obtainedfrom a chlorosulfuron-tolerant line of usitatissimum Crop Dev. A.thaliana and used to transform flax. L. (flax, Centre linseed) A-92 5345Monsanto Resistance to lepidopteran pests through the introductionLycopersicon Company of the cry1Ac gene from Bacillus thuringiensissubsp. esculentum kurstaki. (tomato) A-93 8338 Monsanto Introduction ofa gene sequence encoding the enzyme 1- Lycopersicon Companyaminocyclopropane-1-carboxylic acid deaminase esculentum (ACCd) thatmetabolizes the precursor of the fruit (tomato) ripening hormoneethylene. A-94 1345-4 DNA Plant Delayed ripening tomatoes produced byinserting an Lycopersicon Technology additional copy of a truncated,gene encoding 1- esculentum Corporation aminocyclopropane-1-carboxylicacid (ACC) synthase, (tomato) which resulted in downregulation of theendogenous ACC synthase and reduced ethylene accumulation. A-95 35 1 NAgritope Inc. Introduction of a gene sequence encoding the enzyme S-Lycopersicon adenosylmethionine hydrolase that metabolizes theesculentum precursor of the fruit ripening hormone ethylene. (tomato)A-96 B, Da, F Zeneca Seeds Delayed softening tomatoes produced byinserting a Lycopersicon truncated version of the polygalacturonaseesculentum (PG)-encoding gene in the sense or anti-sense (tomato)orientation in order to reduce expression of the endogenous PG gene, andthus reduce pectin degradation. A-97 FLAVR SAVR Calgene Inc. Delayedsoftening tomatoes produced by inserting an Lycopersicon additional copyof the polygalacturonase (PG)-encoding esculentum gene in the anti-senseorientation in order to reduce (tomato) expression of the endogenous PGgene and thus reduce pectin degradation. A-98 J101, J163 MonsantoGlyphosate herbicide-tolerant alfalfa (Lucerne) produced MedicagoCompany und by inserting a gene encoding the enzyme 5- sativa ForageGenetics enolypyruvylshikimate-3-phosphate synthase (EPSPS) (alfalfa)International from the CP4 strain of Agrobacterium tumefaciens. A-99C/F/93/08-02 Societe National Tolerance to the herbicides bromoxynil andioxynil by Nicotiana d'Exploitation incorporation of the nitrilase genefrom Klebsiella tabacum L. des Tabacs et pneumoniae. (tobacco)Allumettes A-100 Vector 21-41 Vector Tobacco Reduced nicotine contentthrough introduction of a Nicotiana Inc. second copy of the tobaccoquinolinic acid tabacum L. phosphoribosyltransferase (QTPase) in theantisense (tobacco) orientation. The NPTII-encoding gene from E. coliwas introduced as a selectable marker to identify transformants. A-101CL121, BASF Inc. Tolerance to the imidazolinone herbicide imazethapyr,Oryza sativa CL141, induced by chemical mutagenesis of the acetolactate(rice) CFX51 synthase (ALS) enzyme using ethyl methanesulfonate (EMS).A-102 GAT-OS2 Glufosinate tolerance; WO 01/83818 Oryza sativa (rice)A-103 GAT-OS3 Glufosinate tolerance; US 2008-289060 Oryza sativa (rice)A-104 IMINTA-1, BASF Inc. Tolerance to imidazolinone herbicides inducedby Oryza sativa IMINTA-4 chemical mutagenesis of the acetolactatesynthase (ALS) (rice) enzyme using sodium azide. A-105 LLRICE06, AventisGlufosinate ammonium herbicide-tolerant rice produced Oryza sativaLLRICE62 CropScience by inserting a modified phosphinothricin (rice)acetyltransferase (PAT)-encoding gene from the soil bacteriumStreptomyces hygroscopicus. A-106 LLRICE601 Bayer Crop- Glufosinateammonium herbicide-tolerant rice produced Oryza sativa Science byinserting a modified phosphinothricin (rice) (Aventis acetyltransferase(PAT)-encoding gene from the soil CropScience bacterium Streptomyceshygroscopicus. (AgrEvo)) A-107 PE-7 Insect resistance (Cry1Ac); WO2008/114282 Oryza sativa (rice) A-108 PWC16 BASF Inc. Tolerance to theimidazolinon herbicide imazethapyr, Oryza sativa induced by chemicalmutagenesis of the acetolactate (rice) synthase (ALS) enzyme using ethylmethanesulfonate (EMS). A-109 TT51 Insect resistance (Cry1Ab/Cry1Ac);CN1840655 Oryza sativa (rice) A-110 C5 United States Plum pox virus(PPV)-resistant plum tree produced Prunus Department of throughAgrobacterium-mediated transformation with a domestica Agriculture -coat protein (CP) gene from the virus. (plum) Agricultural ResearchService EH92-527 BASF Plant Crop composition; Amflora; Unique EUidentifier: BPS-25271-9 Science A-111 ATBT04-6, Monsanto Colorado potatobeetle-resistant potatoes produced by Solanum ATBT04-27, Companyinserting the cry3A gene from Bacillus thuringiensis tuberosumATBT04-30, (subsp. tenebrionis). L. (potato) ATBT04-31, ATBT04-36,SPBT02-5, SPBT02-7 A-112 BT6, BT10, Monsanto Colorado potatobeetle-resistant potatoes produced by Solanum BT12, BT16, Companyinserting the cry3A gene from Bacillus thuringiensis tuberosum BT17,BT18, (subsp. tenebrionis). L. (potato) BT23 A-113 RBMT15-101, MonsantoColorado potato beetle- and potato Y-virus (PVY)- Solanum SEMT15-02,Company resistant potatoes produced by inserting the cry3A genetuberosum SEMT15-15 from Bacillus thuringiensis (subsp. tenebrionis) andthe L. (potato) coat protein-encoding gene from PVY. A-114 RBMT21-129,Monsanto Colorado potato beetle- and potato leaf roll virus SolanumRBMT21-350, Company (PLRV)-resistant potatoes produced by inserting thetuberosum RBMT22-082 cry3A gene from Bacillus thuringiensis (subsp. L.(potato) tenebrionis) and the replicase-encoding gene from PLRV. A-115AP205CL BASF Inc. Selection for a mutagenized version of the enzymeTriticum acetohydroxy acid synthase (AHAS), also known as aestivumacetolactate synthase (ALS) or acetolactate pyruvate (wheat) lyase.A-116 AP602CL BASF Inc. Selection for a mutagenized version of theenzyme Triticum acetohydroxy acid synthase (AHAS), also known asaestivum acetolactate synthase (ALS) or acetolactate pyruvate (wheat)lyase. A-117 BW255-2, BASF Inc. Selection for a mutagenized version ofthe enzyme Triticum BW238-3 acetohydroxy acid synthase (AHAS), alsoknown as aestivum acetolactate synthase (ALS) or acetolactate pyruvate(wheat) lyase. A-118 BW7 BASF Inc. Tolerance to imidazolinone herbicidesinduced by Triticum chemical mutagenesis of the acetohydroxy acidsynthase aestivum (AHAS) gene using sodium azide. (wheat) A-119 Event 1Fusarium resistance (trichothecene 3-O- Triticum cetyltransferase); CA2561992 aestivum (wheat) A-120 JOPLIN1 Disease (fungal) resistance(trichothecene 3-O- Triticum acetyltransferase); US 2008064032 aestivum(wheat) A-121 MON71800 Monsanto Glyphosate-tolerant wheat varietyproduced by inserting Triticum Company a modified5-enolpyruvylshikimate-3-phosphate aestivum synthase (EPSPS)-encodinggene from the CP4 strain of (wheat) the soil bacterium Agrobacteriumtumefaciens. A-122 SWP965001 Cyanamid Crop Selection for a mutagenizedversion of the enzyme Triticum Protection acetohydroxy acid synthase(AHAS), also known as aestivum acetolactate synthase (ALS) oracetolactate pyruvate (wheat) lyase. A-123 Teal 11A BASF Inc. Selectionfor a mutagenized version of the enzyme Triticum acetohydroxy acidsynthase (AHAS), also known as aestivum acetolactate synthase (ALS) oracetolactate pyruvate (wheat) lyase. A-124 176 Syngenta Seeds,Insect-resistant maize produced by inserting the cry1Ab Zea mays Inc.gene from Bacillus thuringiensis subsp. kurstaki. The L. (maize) geneticmodification affords resistance to attack by the European Corn Borer(ECB). A-125 3272 Self-processing corn (alpha-amylase); US 2006-230473Zea mays L. (maize) A-126 3751IR Pioneer Hi-Bred Selection of somaclonalvariants by culture of embryos Zea mays International onimidazolinone-containing media. L. (maize) Inc. A-127 676, 678, 680Pioneer Hi-Bred Male-sterile and glufosinate ammonium herbicide- Zeamays International tolerant maize produced by inserting genes encodingL. (maize) Inc. DNA adenine methylase and phosphinothricinacetyltransferase (PAT) from Escherichia coli and Streptomycesviridochromogenes. A-128 ACS-ZMØØ3- Bayer Crop- Stacked insect-resistantand herbicide-tolerant maize Zea mays 2 × MON- Science hybrid derivedfrom conventional cross-breeding of the L. (maize) ØØ81Ø-6 (Aventisparental lines T25 (OECD identifier: ACS-ZMØØ3-2) CropScience and MON810(OECD identifier: MON-ØØ81Ø-6). (AgrEvo)) A-129 B16 Glufosinateresistance; US 2003-126634 Zea mays L. (maize) A-130 B16 (DLL25) DekalbGenetics Glufosinate ammonium herbicide-tolerant maize Zea maysCorporation produced by inserting the gene encoding L. (maize)phosphinothricin acetyltransferase (PAT) from Streptomyceshygroscopicus. A-131 BT11 Syngenta Seeds, Insect-resistant andherbicide-tolerant maize produced Zea mays (X4334CBR, Inc. by insertingthe cry1Ab gene from Bacillus thuringiensis L. (maize) X4734CBR) subsp.kurstaki, and the phosphinothricin N- acetyltransferase (PAT)-encodinggene from S. viridochromogenes. A-132 BT11 × Syngenta Seeds, Stackedinsect-resistant and herbicide-tolerant maize Zea mays MIR604 Inc.produced by conventional cross-breeding of parental L. (maize) linesBT11 (OECD unique identifier: SYN-BTØ11-1) and MIR604 (OECD uniqueidentifier: SYN-IR6Ø5-5). Resistance to the European Corn Borer andtolerance to the herbicide glufosinate ammonium (Liberty) is derivedfrom BT11, which contains the cry1Ab gene from Bacillus thuringiensissubsp. kurstaki, and the phosphinothricin N-acetyltransferase(PAT)-encoding gene from S. viridochromogenes. Corn rootworm- resistanceis derived from MIR604 which contains the mcry3A-gene from Bacillusthuringiensis. A-133 BT11 × Syngenta Seeds, Stacked insect-resistant andherbicide-tolerant maize Zea mays MIR604 × Inc. produced by conventionalcross-breeding of parental L. (maize) GA21 lines BT11 (OECD uniqueidentifier: SYN-BTØ11-1), MIR604 (OECD unique identifier: SYN-IR6Ø5-5)and GA21 (OECD unique identifier: MON- Ø Ø Ø21-9). Resistance to theEuropean Corn Borer and tolerance to the herbicide glufosinate ammonium(Liberty) is derived from BT11, which contains the cry1Ab gene fromBacillus thuringiensis subsp. kurstaki, and the phosphinothricinN-acetyltransferase (PAT)-encoding gene from S. viridochromogenes. Cornrootworm- resistance is derived from MIR604 which contains the mcry3Agene from Bacillus thuringiensis. Tolerance to glyphosate herbicide isderived from GA21 which contains a modified EPSPS gene from maize. A-134CBH-351 Aventis Insect-resistant and glufosinate ammonium herbicide- Zeamays CropScience tolerant maize developed by inserting the genes L.(maize) encoding Cry9C protein from Bacillus thuringiensis subsp.tolworthi and phosphinothricin acetyltransferase (PAT) from Streptomyceshygroscopicus. A-135 DAS-06275-8 DOW Lepidopteran insect-resistant andglufosinate ammonium Zea mays AgroSciences herbicide-tolerant maizevariety produced by inserting L. (maize) LLC the cry1F gene fromBacillus thuringiensis var. aizawai and the phosphinothricinacetyltransferase (PAT) from Streptomyces hygroscopicus. A-136DAS-59122-7 DOW Corn rootworm-resistant maize produced by inserting Zeamays AgroSciences the cry34Ab1 and cry35Ab1 genes from the PS149B1 L.(maize) LLC and strain of Bacillus thuringiensis. The PAT-encoding genePioneer Hi-Bred from Streptomyces viridochromogenes was introducedInternational as a selectable marker; US 2006-070139 Inc. A-137DAS-59122-7 × DOW Stacked insect-resistant and herbicide-tolerant maizeZea mays NK603 AgroSciences produced by conventional cross-breeding ofparental L. (maize) LLC and lines DAS-59122-7 (OECD unique identifier:DAS- Pioneer Hi-Bred 59122-7) with NK603 (OECD unique identifier: MON-International ØØ6Ø3-6). Corn rootworm-resistance is derived from Inc.line DAS-59122-7 which contains the cry34Ab1 and cry35Ab1 genes from thePS149B1 strain of Bacillus thuringiensis. Tolerance to glyphosateherbicide is derived from NK603. A-138 DAS-59122-7 × DOW Stackedinsect-resistant and herbicide-tolerant maize Zea mays TC1507 ×AgroSciences produced by conventional cross-breeding of parental L.(maize) NK603 LLC and lines DAS-59122-7 (OECD unique identifier: DAS-Pioneer Hi-Bred 59122-7) and TC1507 (OECD unique identifier DAS-International Ø15Ø7-1) with NK603 (OECD unique identifier: MON- Inc.ØØ6Ø3-6). Corn rootworm-resistance is derived from line DAS-59122-7,which contains the cry34Ab1 and cry35Ab1 genes from the PS149B1 strainof Bacillus thuringiensis. Lepidopteran resistance and tolerance toglufosinate ammonium herbicide are derived from TC1507. Tolerance toglyphosate herbicide is derived from NK603. A-139 DAS-Ø15Ø7-1 × DOWStacked insect-resistant and herbicide-tolerant maize Zea maysMON-ØØ6Ø3-6 AgroSciences derived from conventional cross-breeding of theparental L. (maize) LLC lines 1507 (OECD identifier: DAS-Ø15Ø7-1) andNK603 (OECD identifier: MON-ØØ6Ø3-6). A-140 DBT418 Dekalb GeneticsInsect-resistant and glufosinate ammonium herbicide- Zea maysCorporation tolerant maize developed by inserting genes encoding L.(maize) Cry1AC protein from Bacillus thuringiensis subsp kurstaki andphosphinothricin acetyltransferase (PAT) from Streptomyceshygroscopicus. A-141 DK404SR BASF Inc. Somaclonal variants with amodified acetyl-CoA- Zea mays carboxylase (ACCase) were selected byculture of L. (maize) embryos on sethoxydim-enriched medium. A-142DP-098140-6 Glyphosate tolerance/ALS inhibitor tolerance; Zea mays WO2008/112019 L. (maize) A-143 DP-Ø9814Ø-6 Pioneer Hi-Bred Maize line98140 was genetically engineered to express Zea mays (Event 98140)International the GAT4621 (glyphosate acetyltransferase) and ZM- L.(maize) Inc. HRA (modified maize version of a acetolactate synthase)proteins. The GAT4621 protein, encoded by the gat4621 gene, conferstolerance to glyphosate-containing herbicides by acetylating glyphosateand thereby rendering it non-phytotoxic. The ZM-HRA protein, encoded bythe zm-hra gene, confers tolerance to the ALS-inhibiting class ofherbicides. A-144 Event 3272 Syngenta Seeds, Maize line expressing aheat-stable alpha-amylase gene Zea mays Inc. amy797E for use in thedry-grind ethanol production L. (maize) process. The phosphomannoseisomerase gene from E. coli was used as a selectable marker. A-145EXP1910IT Syngenta Seeds, Tolerance to the imidazolinone herbicideimazethapyr, Zea mays Inc. (formerly induced by chemical mutagenesis ofthe acetolactate L. (maize) Zeneca Seeds) synthase (ALS) enzyme usingethyl methanesulfonate(EMS). A-146 FI117 Glyphosate resistance; U.S.Pat. No. 6,040,497 Zea mays L. (maize) A-147 GA21 Monsanto Induction, bygene-gun bombardment, of a modified 5- Zea mays Companyenolpyruvylshikimate-3-phosphate synthase (EPSPS), an L. (maize) enzymeinvolved in the shikimate biosynthesis pathway for the production of thearomatic amino acids. A-148 GAT-ZM1 Glufosinate tolerance; WO 01/51654Zea mays L. (maize) A-149 GG25 Glyphosate resistance; U.S. Pat. No.6,040,497 Zea mays L. (maize) A-150 GJ11 Glyphosate resistance; U.S.Pat. No. 6,040,497 Zea mays L. (maize) A-151 IT Pioneer Hi-BredTolerance to the imidazolinone herbicide imazethapyr, Zea maysInternational was obtained by in vitro selection of somaclonal L.(maize) Inc. variants. A-152 LY038 Monsanto Altered amino acidcomposition, specifically elevated Zea mays Company levels of lysine,through the introduction of the cordapA L. (maize) gene, derived fromCorynebacterium glutamicum, encoding the enzyme dihydrodipicolinatesynthase (cDHDPS); U.S. Pat. No. 7,157,281 A-153 MIR162 Insectresistance; WO 2007142840 Zea mays L. (maize) A-154 MIR604 SyngentaSeeds, Corn rootworm-resistant maize was produced by Zea mays Inc.transformation with a modified cry3A gene. The L. (maize) phosphomannoseisomerase gene from E. coli was used as a selectable marker; (Cry3a055);EP 1 737 290 A-155 MIR604 × Syngenta Seeds, Stacked insect-resistant andherbicide-tolerant maize Zea mays GA21 Inc. produced by conventionalcross-breeding of parental L. (maize) lines MIR604 (OECD uniqueidentifier: SYN-IR60Ø5-5) and GA21 (OECD unique identifier: MON-ØØØ21-9). Corn rootworm-resistance is derived from MIR604 which containsthe mcry3A gene from Bacillus thuringiensis. Tolerance to glyphosateherbicide is derived from GA21. A-156 MON80100 Monsanto Insect-resistantmaize produced by inserting the cry1Ab Zea mays Company gene fromBacillus thuringiensis subsp. kurstaki. The L. (maize) geneticmodification affords resistance to attack by the European Corn Borer.A-157 MON802 Monsanto Insect-resistant and glyphosate herbicide-tolerantmaize Zea mays Company produced by inserting the genes encoding theCry1Ab L. (maize) protein from Bacillus thuringiensis and the 5-enolpyruvylshikimate-3-posphate synthase (EPSPS) from the CP4 strain ofA. tumefaciens. A-158 MON809 Pioneer Hi-Bred Resistance to European CornBorer (Ostrinia nubilalis) Zea mays International by introduction of asynthetic cry1Ab gene. Glyphosate L. (maize) Inc. resistance viaintroduction of the bacterial version of a plant enzyme,5-enolpyruvylshikimat-3-phosphate synthase (EPSPS). A-159 MON810Monsanto Insect-resistant maize produced by inserting a truncated Zeamays Company form of the cry1Ab gene from Bacillus thuringiensis L.(maize) subsp. kurstaki HD-1. The genetic modification affordsresistance to attack by the European Corn Borer (ECB); US 2004-180373A-160 MON810 × Monsanto Stacked insect-resistant and glyphosate-tolerantmaize Zea mays MON88017 Company derived from conventional cross-breedingof the parental L. (maize) lines MON810 (OECD identifier: MON-ØØ81Ø-6)and MON88017 (OECD identifier: MON-88Ø17-3). European Corn Borer (ECB)resistance is derived from a truncated form of the cry1Ab gene fromBacillus thuringiensis subsp. kurstaki HD-1, present in MON810. Cornrootworm-resistance is derived from the cry3Bb1 gene from the EG4691strain of Bacillus thuringiensis subspecies kumamotoensis present inMON88017. Glyphosate tolerance is derived from a 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)- encoding gene fromthe CP4 strain of Agrobacterium tumefaciens present in MON88017. A-161MON832 Monsanto Introduction, by gene-gun bombardment, of glyphosate Zeamays Company oxidase (GOX) and a modified 5-enolpyruvylshikimate- L.(maize) 3-phosphate synthase (EPSPS), an enzyme involved in theshikimate biosynthesis pathway for the production of the aromatic aminoacids. A-162 MON863 Monsanto Corn rootworm-resistant maize produced byinserting Zea mays Company the cry3Bb1 gene from Bacillus thuringiensissubsp. L. (maize) kumamotoensis. A-163 MON87460 Drought tolerance; waterdeficit tolerance; WO Zea mays 2009/111263 L. (maize) A-164 MON88017Monsanto Corn rootworm-resistant maize produced by inserting Zea maysCompany the cry3Bb1 gene from the EG4691 strain of Bacillus L. (maize)thuringiensis subsp. kumamotoensis. Glyphosate tolerance was derived byinserting a 5- enolpyruvylshikimate-3-phosphate synthase (EPSPS)-encoding gene from the CP4 strain of Agrobacterium tumefaciens; WO2005059103 A-165 MON89034 Monsanto Maize event expressing two differentinsecticidal Zea mays Company proteins from Bacillus thuringiensisproviding resistance L. (maize) to a number of lepidopteran pests;insect resistance (Lipidoptera-Cry1A.105-Cry2Ab); WO 2007140256 A-166MON89034 × Monsanto Stacked insect-resistant and glyphosate-tolerantmaize Zea mays MON88017 Company derived from conventional cross-breedingof the parental L. (maize) lines MON89034 (OECD identifier: MON-89Ø34-3) and MON88017 (OECD identifier: MON-88Ø17-3). Resistance tolepidopteran insects is derived from two cry genes present in MON89043.Corn rootworm- resistance is derived from a single cry gene andglyphosate tolerance is derived from a 5-enolpyruylshikimate-3-phosphate synthase (EPSPS)- encoding gene fromAgrobacterium tumefaciens present in MON88017. A-167 MON-ØØ6Ø3- MonsantoStacked insect-resistant and herbicide-tolerant maize Zea mays 6 × MON-Company hybrid derived from conventional cross-breeding of the L.(maize) ØØ81Ø-6 parental lines NK603 (OECD identifier: MON-ØØ6Ø3- 6) andMON810 (OECD identifier: MON-Ø81Ø-6). A-168 MON-ØØ81Ø- Monsanto Stackedinsect-resistant and increased lysine-content Zea mays 6 × LY038 Companymaize hybrid derived from conventional cross-breeding L. (maize) of theparental lines MON810 (OECD identifier: MON- ØØ81Ø-6) and LY038 (OECidentifier: REN-ØØØ38- 3). A-169 MON-ØØ863- Monsanto Stackedinsect-resistant and herbicide-tolerant maize Zea mays 5 × MON- Companyhybrid derived from conventional cross-breeding of the L. (maize)ØØ6Ø3-6 parental lines MON863 (OECD identifier: MON- ØØ863-5) and NK603(OECD identifier: MON-ØØ6Ø3- 6). A-170 MON-ØØ863- Monsanto Stackedinsect-resistant maize hybrid derived from Zea mays 5 × MON Companyconventional cross-breeding of the parental lines L. (maize) ØØ81Ø-6MON863 (OECD identifier: MON-Ø863-5) und MON810 (OECD identifier:MON-ØØ81Ø-6) A-171 MON-ØØ863- Monsanto Stacked insect-resistant andherbicide-tolerant maize Zea mays 5 × MON- Company hybrid derived fromconventional cross-breeding of the L. (maize) Ø81Ø-6 × stacked hybridsMON-ØØ863-5 × MON-ØØ81Ø-6 and MON-ØØ6Ø3-6 NK603 (OECD identifier:MON-ØØ6Ø3-6). A-172 MON-ØØØ21- Monsanto Stacked insect-resistant andherbicide-tolerant maize Zea mays 9 × MON- Company hybrid derived fromconventional cross-breeding of the L. (maize) ØØ81Ø-6 parental linesGA21 (OECD identifier: MON-ØØØ21-9) and MON810 (OECD identifier:MON-ØØ81Ø-6). A-173 MS3 Bayer Crop- Male sterility caused by expressionof the barnase Zea mays Science ribonuclease gene from Bacillusamyloliquefaciens; PPT L. (maize) (Aventis resistance was obtained viaPPT acetyltransferase (PAT). CropScience (AgrEvo)) A-174 MS6 Bayer Crop-Male sterility caused by expression of the barnase Zea mays Scienceribonuclease gene from Bacillus amyloliquefaciens; PPT L. (maize)(Aventis resistance was attained via PPT acetyltransferase (PAT).CropScience (AgrEvo)) A-175 NK603 Monsanto Introduction by gene-gunbombardment of a modified 5- Zea mays Companyenolpyruvylshikimate-3-phosphate synthase (EPSPS), an L. (maize) enzymeinvolved in the shikimate biosynthesis pathway for the production of thearomatic amino acids. A-176 PV-ZMGT32 Glyphosate tolerance; US2007-056056 Zea mays (NK603) L. (maize) A-177 PV-ZMGT32 Glyphosatetolerance; US 2007292854 Zea mays (nk603) L. (maize) A-178 PV-ZM1R13Insect resistance (Cry3Bb); US 2006-095986 Zea mays (MON863) L. (maize)A-179 SYN-BTØ11- Syngenta Seeds, Stacked insect-resistant andherbicide-tolerant maize Zea mays 1 × MON- Inc. produced by conventionalcross-breeding of parental L. (maize) ØØØ21-9 lines BT11 (OECD uniqueidentifier: SYN-BTØ11-1) and GA21 (OECD unique identifier: MON-ØØØ21-9).A-180 T14, T25 Bayer Glufosinate herbicide-tolerant maize produced byZea mays CropScience inserting the phosphinothricin N-acetyltranferase(PAT)- L. (maize) (Aventis encoding gene from the aerobic actinomyceteCropScience Streptomyces viridochromogenes. (AgrEvo)) A-181 TC1507Mycogen (c/o Insect-resistant and glufosinate ammonium Zea mays Dowherbicide-tolerant maize produced by inserting the cry1F L. (maize)AgroSciences); gene from Bacillus thuringiensis var. aizawai and thePioneer (c/o phosphinothricin N-acetyltransferase-encoding gene Dupont)from Streptomyces viridochromogenes. A-182 TC1507 × DOW Stackedinsect-resistant and herbicide-tolerant maize Zea mays DAS-59122-7AgroSciences produced by conventional cross-breeding of parental L.(maize) LLC and lines TC1507 (OECD unique identifier: DAS-Ø15Ø7-1)Pioneer Hi-Bred with DAS-59122-7 (OECD unique identifier: DAS-International 59122-7). Resistance to lepidopteran insects is derivedInc. from TC1507 due to the presence of the cry1F gene from Bacillusthuringiensis var. aizawai. Corn rootworm- resistance is derived fromline DAS-59122-7 which contains the cry34b1 and cry35Ab1 genes fromBacillus. Thuringiensis strain PS149B1. Tolerance to glufosinateammonium herbicide is derived from TC1507 from the phosphinothricinN-acetyltransferase- encoding gene from Streptomyces viridochromogenes.A-183 VIP1034 Insect resistance; WO 03/052073 Zea mays L. (maize)

In one embodiment of the invention the plants B-1 to B-129 of table B,in total or in part, or propagation material of said plants, is treatedor contacted with the active ingredient combinations of the invention,alone or in the form of compositions comprising an active ingredientcombination.

TABLE B Non-exhaustive list of transgenic plants to carry out theinvention from the APHIS database of the United States Department ofAgriculture (USDA). The database can be found on:http://www.aphis.usda.govianimal_welfarelefoia/index.shtml. EA finalExtension of Transformation conclusion & No. Petition Petition***Institution Plant Event or Line determination B-1 10-070-01p VirginiaTech Peanut Sclerotinia N70, P39 and blight-resistant W171 B-209-349-01p Dow Soya bean 2,4-D- and DAS-68416-4 AgroSciences glufosinatetolerance B-3 09-328-01p Bayer Crop Soya bean glyphosate and FG72Science isoxaflutole tolerance B-4 09-233-01p Dow Maize 2,4-D andACCase- DAS-40278-9 inhibitor tolerance B-5 09-201-01p Monsanto Soyabean improved fatty acid MON-87705-6 profile B-6 09-183-01p MonsantoSoya bean stearidonic acid MON-87769 production B-7 09-082-01p MonsantoSoya bean Lepidoteran MON 87701 resistance B-8 09-063-01p Stine SeedMaize Glyphosate HCEM485 tolerance B-9 09-055-01p Monsanto Maize Droughttolerance MON 87460 B-10 09-015-01p BASF Plant Soya bean ImidazlinonBPS-CV127-9 Science, LLC tolerance Soya bean B-11 08-366-01p ArborGenEucalyptus Freeze tolerance, ARB-FTE?-08 fertility altered B-1208-340-01p Bayer Cotton Glufosinate T304-40XGHB119 tolerance, insectresistance B-13 08-338-01p Pioneer Maize Male sterility, DP-32138-1fertility restored, visual marker B-14 08-315-01p Florigene Rose Alteredflower IFD-52401-4 and color IFD-52901-9 B-15 07-108-01p Syngenta CottonLepidopteran COT67B resistance B-16 06-354-01p Pioneer Soya bean Higholeic acid DP-305423-1 B-17 content B-18 05-280-01p Syngenta MaizeTermostable 3272 B-19 alpha-arnylase B-20 04-110-01p Monsanto & AlfalfaGlyphosate J101, J163 B-21 Forage Genetics tolerance B-22 B-23 B-2403-104-01p Monsanto & Creeping Glyphosate ASR368 B-25 Scotts bentgrasstolerance B-26 B-27 B-28 B-29 B-30 07-253-01p Syngenta MaizeLepidopteran MIR-162 Maize B-31 resistance B-32 07-152-01p Pioneer MaizeGlyphosate & DP-098140-6 B-33 imidazolinone tolerance B-34 04-337-01pUniveristy of Papaya Papaya ringspot X17-2 B-35 Florida virus-resistantB-36 06-332-01p Bayer Cotton Glyphosate GHB614 B-37 CropSciencetolerance B-38 06-298-01p Monsanto Maize European Corn MON 89034 B-39Borer resistance B-40 06-271-01p Pioneer Soya bean Glyphosate & 356043B-41 acetolactate (DP-356043-5) synthase tolerance B-42 06-234-01p98-329-01p Bayer Rice phosphinothricin LLRICE601 B-43 CropSciencetolerance B-44 06-178-01p Monsanto Soya bean Glyphosate MON 89788 B-45tolerance B-46 04-362-01p Syngenta Maize Corn MIR604 B-47rootworm-protected B-48 B-49 04-264-01p ARS Plum Plum Pox C5 B-50virus-resistant B-51 04-229-01p Monsanto Maize High lysine content LY038B-52 B-53 04-125-01p Monsanto Maize Corn rootworm- 88017 B-54 resistanceB-55 04-086-01p Monsanto Cotton Glyphosate MON 88913 B-56 tolerance B-57B-58 03-353-01p Dow Maize Corn rootworm- 59122 B-59 resistance B-6003-323-01p Monsnato Sugar beet Glyphosate H7-1 B-61 tolerance B-6203-181-01p 00-136-01p Dow Maize Lepidopteran TC-6275 B-63 resistance &phosphinothricin tolerance B-64 03-155-01p Syngenta Cotton LepidopteranCOT 102 B-65 resistance B-66 03-036-01p Mycogen/Dow Cotton Lepidopteran281-24-236 B-67 resistance B-68 03-036-02p Mycogen/Dow CottonLepidopteran 3006-210-23 B-69 resistance B-70 02-042-01p Aventis CottonPhosphinothricin LLCotton25 tolerance B-71 01-324-01p 98-216-01pMonsanto Oilseed Glyphosate RT200 rape tolerance B-72 01-206-01p98-278-01p Aventis Oilseed Phosphinothricin- MS1 & RF1/RF2 rapetolerance & pollination control B-73 01-206-02p 97-205-01p AventisOilseed Phosphinothricin Topas 19/2 rape tolerance B-74 01-137-01pMonsanto Maize Corn rootworm- MON 863 resistance B-75 01-121-01p VectorTobacco Reduced nicotine Vector 21-41 content B-76 00-342-01p MonsantoCotton Lepidopteran Cotton Event resistance 15985 B-77 00-136-01pMycogen c/o Maize Lepidopteran Line 1507 Dow & Pioneer resistance &phosphinothricin tolerance B-78 00-011-01p 97-099-01p Monsanto MaizeGlyphosate NK603 tolerance B-79 99-173-01p 97-204-01p Monsanto PatatoPLRV & CPB RBMT22-82 resistance B-80 98-349-01p 95-228-01p AgrEvo MaizePhosphinothricin M86 tolerance and male sterility B-81 98-335-01p U. ofFlax Tolerant to soil CDC Triffid Saskatchewan residues of sulfonylureaherbicide B-82 98-329-01p AgrEvo Rice Phosphinothricin LLRICE06,tolerance LLRICE62 B-83 98-278-01p AgrEvo Oilseed Phosphinothricin MS8 &RF3 rape tolerance & pollination control B-84 98-238-01p AgrEvo Soyabean Phosphinothricin GU262 tolerance B-85 98-216-01p Monsanto OilseedGlyphosate RT73 rape tolerance B-86 98-173-01p Novartis Seeds BeetGlyphosate GTSB77 & Monsanto tolerance B-87 98-014-01p 96-068-01p AgrEvoSoya bean Phosphinothricin A5547-127 tolerance B-88 97-342-01p PioneerMaize Male sterility & 676, 678, 680 phosphinothricin tolerance B-8997-339-01p Monsanto Potato CPB & PVY RBMT15-101, resistance SEMT15-01,SEMT15-15 B-90 97-336-01p AgrEvo Beet Phosphinothricin T-120-7 toleranceB-91 97-287-01p Monsanto Tomato Lepidopteran 5345 resistance B-9297-265-01p AgrEvo Maize Phosphinothricin CBH-351 tolerance &Lepidopteran resistance B-93 97-205-01p AgrEvo Oilseed PhosphinothricinT45 rape tolerance B-94 97-204-01p Monsanto Potato CPB & PLRV RBMT21-129& resistance RBMT21-350 B-95 97-148-01p Bejo Cichorium Male sterilityRM3-3, RM3-4, intybus RM3-6 B-96 97-099-01p Monsanto Maize GlyphosateGA21 tolerance B-97 97-013-01p Calgene Cotton Bromoxynil Events 31807 &tolerance & 31808 Lepidopteran resistance B-98 97-008-01p Du Pont Soyabean Oil profile altered G94-1, G94-19, G-168 B-99 96-317-01p MonsantoMaize Glyphosate MON802 tolerance & ECB resistance B-100 96-291-01pDeKalb Maize European Corn DBT418 Borer resistance B-101 96-248-01p92-196-01p Calgene Tomato Fruit ripening 1 additional altered FLAVRSAVRline B-102 96-068-01p AgrEvo Soya bean Phosphinothricin W62, W98,tolerance A2704-12, A2704-21, A5547-35 B-103 96-051-01p Cornell U PapayaPRSV resistance 55-1, 63-1 B-104 96-017-01p 95-093-01p Monsanto MaizeEuropean Corn MON809 & Borer resistance MON810 B-105 95-352-01p AsgrowSummer CMV, ZYMV, CZW-3 squash WMV2 resistance B-106 95-338-01p MonsantoPotato CPB resistance SBT02-5 & -7, ATBT04-6 & -27, -30, -31, -36 B-10795-324-01p Agritope Tomato Fruit ripening 35 1 N altered B-10895-256-01p Du Pont Cotton Sulfonylurea 19-51a resistance B-10995-228-01p Plant Genetic Maize Male Sterile MS3 Systems B-110 95-195-01pNorthrup King Maize European Corn Bt11 Borer resistance B-111 95-179-01p92-196-01p Calgene Tomato Fruit ripening 2 additional altered FLAVRSAVR-lines B-112 95-145-01p DeKalb Maize Phosphinothricin B16 tolerance B-11395-093-01p Monsanto Maize Lepidopteran MON 80100 resistance B-11495-053-01p Monsanto Tomato Fruit ripening 8338 altered B-115 95-045-01pMonsanto Cotton Glyphosate 1445, 1698 tolerance B-116 95-030-01p92-196-01p Calgene Tomato Fruit ripening 20 additional altered FLAVRSAVRlines B-117 94-357-01p AgrEvo Maize Phosphinothricin T14, T25 toleranceB-118 94-319-01p Ciba Seeds Maize Lepidopteran Event 176 resistanceB-119 94-308-01p Monsanto Cotton Lepidopteran 531, 757, 1076 resistanceB-120 94-290-01p Zeneca & Tomato Fruit B, Da, F Petoseedpolygalacturonase level decreased B-121 94-257-01p Monsanto PotatoColeopteran BT6, BT10, BT12, resistance BT16, BT17, BT18, BT23 B-12294-230-01p 92-196-01p Calgene Tomato Fruit ripening 9 additional alteredFLAVRSAVR lines B-123 94-228-01p DNA Plant Tech Tomato Fruit ripening1345-4 altered B-124 94-227-01p 92-196-01p Calgene Tomato Fruit ripeningLine N73 1436- altered 111 B-125 94-090-01p Calgene Oilseed Oil profilealtered Pcgn3828- rape 212/86-18 & 23 B-126 93-258-01p Monsanto Soyabean Glyphosate 40-3-2 tolerance B-127 93-196-01p Calgene CottonBromoxynil BXN tolerance B-128 92-204-01p Upjohn Summer WMV2 & ZYMVZW-20 squash resistance B-129 92-196-01p Calgene Tomato Fruit ripeningFLASVR SAVR altered Abbreviations used in this table: CMV—cucumbermosaic virus, CPB—Colorado potato beetle, PLRV—potato leafroli Virus,PRSV—papaya ringspot virus, PVY—potato virus Y, WMV2—watermelon mosaicVials 2 ZYMV—zucchini yellow mosaic virus

In one embodiment the plants which comprise a transgenic event as perD-1 to D-48 of table D or express such a trait, in whole or in part, orpropagation material of these plants, are or is contacted or treatedwith the active ingredient combinations of the invention, alone or inthe form of compositions which comprise an active ingredientcombination.

TABLE D Non-exhaustive list of transgenic events and traits theinvention can be worked on, with reference to patent applications. No.Plant species Transgenic event Trait Patent reference D-1 MaizePV-ZMGT32 (NK603) Glyphosate tolerance US 2007-056056 D-2 Maize MIR604Insect resistance (Cry3a055) EP-A 1 737 290 D-3 Maize LY038 High lysinecontent U.S. Pat. No. 7,157,281 D-4 Maize 3272 Self-processing maize US2006-230473 (alpha-amylase) D-5 Maize PV-ZMIR13 (MON863) Insectresistance (Cry3Bb) US 2006-095986 D-6 Maize DAS-59122-7 Insectresistance US 2006-070139 (Cry34Ab1/Cry35Ab1) D-7 Maize TC1507 Insectresistance (Cry1F) U.S. Pat. No. 7,435,807 D-8 Maize MON810 Insectresistance (Cry1Ab) US 2004-180373 D-9 Maize VIP1034 Insect resistanceWO 03/052073 D-10 Maize B16 Glufosinate resistance US 2003-126634 D-11Maize GA21 Glyphosate resistance U.S. Pat. No. 6,040,497 D-12 Maize GG25Glyphosate resistance U.S. Pat. No. 6,040,497 D-13 Maize GJ11 Glyphosateresistance U.S. Pat. No. 6,040,497 D-14 Maize FI117 Glyphosateresistance U.S. Pat. No. 6,040,497 D-15 Maize GAT-ZM1 Glufosinatetolerance WO 01/51654 D-16 Maize DP-098140-6 Glyphosate tolerance/ALS-WO 2008/112019 inhibitor tolerance D-17 Wheat Event 1 Fusariumresistance CA 2561992 (trichothecene 3-O- acetyltransferase) D-18 Sugarbeet T227-1 Glyphosate tolerance US 2004-117870 D-19 Sugar beet H7-1Glyphosate tolerance WO 2004-074492 D-20 Soya bean MON89788 Glyphosatetolerance US 2006-282915 D-21 Soya bean A2704-12 Glufosinate toleranceWO 2006/108674 D-22 Soya bean A5547-35 Glufosinate tolerance WO2006/108675 D-23 Soya bean DP-305423-1 High oleic acid/ALS- WO2008/054747 inhibitor tolerance D-24 Rice GAT-OS2 Glufosinate toleranceWO 01/83818 D-25 Rice GAT-OS3 Glufosinate tolerance US 2008-289060 D-26Rice PE-7 Insect resistance (Cry1Ac) WO 2008/114282 D-27 Oilseed rapeMS-B2 Male sterility WO 01/31042 D-28 Oilseed rape MS-BN1/RF-BN1 Malesterility/restoration WO 01/41558 D-29 Oilseed rape RT73 Glyphosateresistance WO 02/36831 D-30 Cotton CE43-67B Insect resistance (Cry1Ab)WO 2006/128573 D-31 Cotton CE46-02A Insect resistance (Cry1Ab) WO2006/128572 D-32 Cotton CE44-69D Insect resistance (Cry1Ab) WO2006/128571 D-33 Cotton 1143-14A Insect resistance (Cry1Ab) WO2006/128569 D-34 Cotton 1143-51B Insect resistance (Cry1Ab) WO2006/128570 D-35 Cotton T342-142 Insect resistance (Cry1Ab) WO2006/128568 D-36 Cotton event3006-210-23 Insect resistance (Cry1Ac) WO2005/103266 D-37 Cotton PV-GHGT07 (1445) Glyphosate tolerance US2004-148666 D-38 Cotton MON88913 Glyphosate tolerance WO 2004/072235D-39 Cotton EE-GH3 Glyphosate tolerance WO 2007/017186 D-40 CottonT304-40 Insect resistance (Cry1Ab) WO2008/122406 D-41 Cotton Cot202Insect resistance (VIP3) US 2007-067868 D-42 Cotton LLcotton25Glufosinate resistance WO 2007/017186 D-43 Cotton EE-GH5 Insectresistance (Cry1Ab) WO 2008/122406 D-44 Cotton event 281-24-236 Insectresistance (Cry1F) WO 2005/103266 D-45 Cotton Cot102 Insect resistance(Vip3A) US 2006-130175 D-46 Cotton MON 15985 Insect resistance US2004-250317 (Cry1A/Cry2Ab) D-47 Bentgrass Asr-368 Glyphosate toleranceUS 2006-162007 D-48 Aubergine EE-1 Insect resistance (Cry1Ac) WO2007/091277

In one embodiment the plants which comprise a transgenic event as perE-1 to E-50 of table E or express such a trait, in whole or in part, orpropagation material of these plants, are or is contacted or treatedwith the active ingredient combinations of the invention, alone or inthe form of compositions which comprise an active ingredientcombination.

TABLE E Non-exhaustive list of transgenic events and traits and theirtrade names. No. Trade name Plant Company Genetically modifiedproperties Additional information E-1 Roundup Beta vulgaris MonsantoGlyphosate tolerance Ready ® (sugar beet) Company E-2 InVigor ® Brassicanapus Bayer Canola rape was genetically modified with the (ArgentineCropScience following result: canola rape) Ø expression of a gene whichconfers tolerance to the herbicide glyfosinate ammonium; Ø introductionof a novel hybrid breeding system for canola rape which is based ongenetically modified male-sterility (MS) and fertility- restorer (RF)lines; Ø expression of a gene for resistance to antibiotics. E-3 LibertyLink ® Brassica napus BayerCrop- Phosphinotricin tolerance (ArgentineScience canola rape) E-4 Roundup Brassica napus Monsanto Glyphosatetolerance Ready ® (canola rape) Company E-5 Clearfield ® (Canola rape)BASF Non-GMO, imazamox tolerance Corporation E-6 Optimum ™ Glycine maxPioneer Hi- Glyphosate and ALS herbicide tolerance GAT ™ L. (soya bean)Bred International, Inc E-7 Roundup Glycine max Monsanto Glyphosatetolerance Ready ® L. (soya bean) Company E-8 Roundup Glycine maxMonsanto Glyphosate tolerance RReady2Yiel ™ L. (soya bean) Company E-9STS ® Glycine max DuPont Sulfonylurea tolerance L. (soya bean) E-10YIELD Glycine max Monsanto GARD ® L. (soya bean) Company E-11 AFD ®Gossypium Bayer The lines include, for example, AFD5062LL, hirsutumCropScience AFD5064F, AFD 5065B2F; AFD seed is available L. (cotton) ina wide range of varieties with integrated technology such as, forexample, the Bollgard ®, Bollgard II, Roundup Ready, Roundup Ready Flexand LibertyLink ® technologies E-12 Bollgard II ® Gossypium Monsanto MON15985 event: Cry2(A)b1; Cry1A(c) hirsutum Company L. (cotton) E-13Bollgard ® Gossypium Monsanto Cry 1Ac hirsutum Company L. (cotton) E-14FiberMax ® Gossypium Bayer hirsutum CropScience L. (cotton) E-15 LibertyLink ® Gossypium Bayer Phosphinotricin tolerance hirsutum CropScience L.(cotton) E-16 Nucotn 33B Gossypium Delta Pine Bt toxin in the lines fromDelta Pine: CrylAc hirsutum and Land L. (cotton) E-17 Nucotn 35BGossypium Delta Pine Bt toxin in the lines from Delta Pine: CrylAchirsutum and Land L. (cotton) E-18 Nucotn ® Gossypium Delta Pine Bttoxin in the lines from Delta Pine hirsutum and Land L. (cotton) E-19PhytoGen ™ Gossypium PhytoGen Seed Comprises varieties which contain,for hirsutum Company, Dow example, Roundup Ready flex, Widestrike L.(cotton) AgroSciences LLC E-20 Roundup Gossypium Monsanto Glyphosatetolerance Ready Flex ® hirsutum Company L. (cotton) E-21 RoundupGossypium Monsanto Glyphosate tolerance Ready ® hirsutum Company L.(cotton) E-22 Widestrike ™ Gossypium Dow Cry1F and Cry1Ac Monsanto/Dowhirsutum AgroSciences L. (cotton) LLC E-23 YIELD Gossypium Monsantohttp://www.garstseed.com/ GARD ® hirsutum CompanyGarstClient/Technology/ L. (cotton) agrisure.aspx E-24 Roundup MedicagoMonsanto Glyphosate tolerance Ready ® sativa (alfalfa) Company E-25Clearfield ® Oryza sativa BASF Non-GMO, imazamox tolerance (rice)Corporation E-26 NewLeaf ® Solanum Monsanto Resistance to infection bypotato leafroll virus tuberosum Company (PLRV) and feeding damage by theColorado L. (potato) beetle Leptinotarsa decemlineata E-27 NewLeaf ®Solanum Monsanto Resistance to infection by potato leafroll virushttp://www.dowagro.com/ plus tuberosum Company (PLRV) and feeding damageby the Colorado phytogen/index.htm L. (potato) beetle Leptinotarsadecemlineata E-28 Protecta ® Solanum tuberosum L. (potato) E-29Clearfield ® Sunflower BASF Non-GMO, imazamox tolerance Corporation E-30Roundup Triticum Monsanto Glyphosate tolerance, NK603 Ready ® aestivumCompany (wheat) E-31 Clearfield ® Wheat BASF Non-GMO, imazamox toleranceCorporation E-32 Agrisure ® Zea mays Syngenta These include AgrisureCB/LL (BT 11 event plus (Family) L. (maize) Seeds, Inc. phosphinotricintolerance as the result of GA21 event); Agrisure CB/LL/RW (Bt 11 event,modified synthetic Cry3A gene, phosphinotricin tolerance as the resultof GA21 event); Agrisure GT (glyphosate tolerance); AgrisureGT/CB/LL(glyphosate tolerance and phosphinotricin tolerance as theresult of GA21 event, Bt 11 event); Agrisure 3000GT (CB/LL/RW/GT:glyphosate and phosphinotricin tolerance as the result of GA21 event; Bt11 event, modified synthetic Cry3A gene); Agrisure GT/RW (glyphosatetolerance, modified synthetic Cry3A gene); Agrisure RW (modifiedsynthetic Cry3A gene); future traits E-33 BiteGard ® Zea mays NovartisSeeds cry1A(b) gene L. (maize) E-34 Bt-Xtra ® Zea mays DEKALB cry1Acgene L. (maize) Genetics Corporation E-35 Clearfield ® Zea mays BASFNon-GMO, imazamox tolerance L. (maize) Corporation E-36 Herculex ® Zeamays Dow (Familie) L. (maize) AgroSciences LLC E-37 IMI ® Zea maysDuPont Imidazolinone tolerance L. (maize) E-38 KnockOut ® Zea maysSyngenta SYN-EV176-9: cry1A(b) gene L. (maize) Seeds, Inc, E-39 Mavera ®Zea mays Renessen High lysine http://www.dowagro.com/ L. (maize) LLCwidestrike/ E-40 NatureGard ® Zea mays Mycogen cry1A(b) gene L. (maize)E-41 Roundup Zea mays Monsanto Glyphosate tolerancehttp://www.starlinkcorn.com/ Ready ® L. (maize) Company starlinkcorn.htmE-42 Roundup Zea mays Monsanto Glyphosate tolerance Ready ®2 L. (maize)Company E-43 SmartStax Zea mays Monsanto Combination of eight genes L.(maize) Company E-44 StarLink ® Zea mays Aventis Cry9c gene L. (maize)CropScience −> Bayer CropScience E-45 STS ® Zea mays DuPont Sulfonylureatolerance L. (maize) E-46 YIELD Zea mays Monsanto Mon810, Cry1Ab1;resistance to the http://www.dowagro.com/ GARD ® L. (maize) CompanyEuropean Corn Borer herculex/about/herculexfamily/ E-47 YieldGard ® Zeamays Monsanto Mon810 × Mon863, dual resistance to Plus L. (maize)Company European Corn Borer and corn rootworm E-48 YieldGard ® Zea maysMonsanto Mon863, Cry3Bb1, resistance to corn Rootworm L. (maize) Companyrootworm E-49 YieldGard ® Zea mays Monsanto Stacked traits VT L. (Maize)Company E-50 YieldMaker ™ Zea mays DEKALB Contains Roundup Ready 2technology, L. (Maize) Genetics YieldGard VT, YieldGard Corn Borer,Corporation YieldGard Rootworm and YieldGard Plus

Transgenic crop plants that can be treated in accordance with theinvention are preferably plants which comprise transformation events(transformation-integration events) or a combination of transformationevents (transformation-integration events) and which, for example, arelisted in the databases for various national or regional registrationauthorities, including event 1143-14A (cotton, insect control, notfiled, described in WO2006/128569); event 1143-51B (cotton, insectcontrol, not filed, described in WO2006/128570); event 1445 (cotton,herbicide tolerance, not filed, described in US2002120964 orWO2002/034946); event 17053 (rice, herbicide tolerance, filed asPTA-9843, described in WO2010/117737); event 17314 (rice, herbicidetolerance, filed as PTA-9844, described in WO2010/117735); event281-24-236 (cotton, insect control-herbicide tolerance, filed asPTA-6233, described in WO2005/103266 or US2005216969); event 3006-210-23(cotton, insect control herbicide tolerance, filed as PTA-6233,described in US2007143876 or WO2005/103266); event 3272 (maize, qualitytrait, filed as PTA-9972, described in WO2006098952 or US2006230473);event 40416 (maize, insect control-herbicide tolerance, filed as ATCCPTA-11508, described in WO2011/075593); event 43A47 (maize, insectcontrol-herbicide tolerance, filed as ATCC PTA-11509, described inWO2011/075595); event 5307 (maize, insect control, filed as ATCCPTA-9561, described in WO2011/077816); event ASR-368 [bent grass,herbicide tolerance, filed as ATCC PTA-4816, described in US2006162007or WO2004053062]; event B16 (maize, herbicide tolerance, not filed,described in US2003126634); event BPS-CV127-9 (soya bean, herbicidetolerance, filed as NCIMB No. 41603, described in WO2010/080829); eventCE43-67B (cotton, insect control, filed as DSM ACC2724, described inUS2009217423 or WO2006/128573); event CE44-69D (cotton, insect control,not filed, described in US20100024077); event CE44-69D (cotton, insectcontrol, not filed, described in WO2006/128571); event CE46-02A (cotton,insect control, not filed, described in WO2006/128572); event COT102(cotton, insect control, not filed, described in US2006130175 orWO2004039986); event COT202 (cotton, insect control, not filed,described in US2007067868 or WO2005054479); event COT203 (cotton, insectcontrol, not filed, described in WO2005/054480); event DAS40278 (maize,herbicide tolerance, filed as ATCC PTA-10244, described inWO2011/022469); event DAS-59122-7 (maize, insect control-herbicidetolerance, filed as ATCC PTA 11384, described in US2006070139); eventDAS-59132 (maize, insect control-herbicide tolerance, not filed,described in WO2009/100188); event DAS68416 (soya bean, herbicidetolerance, filed as ATCC PTA-10442, described in WO2011/066384 orWO2011/066360); event DP-098140-6 (maize, herbicide tolerance, filed asATCC PTA-8296, described in US2009137395 or WO2008/112019); eventDP-305423-1 (soya bean, quality trait, not filed, described inUS2008312082 or WO2008/054747); event DP-32138-1 (maize, hybrid system,filed as ATCC PTA-9158, described in US20090210970 or WO2009/103049);event DP-356043-5 (soya bean, herbicide tolerance, filed as ATCCPTA-8287, described in US20100184079 or WO2008/002872); event EE-1(aubergine, insect control, not filed, described in WO2007/091277);event FI117 (maize, herbicide tolerance, filed as ATCC 209031, describedin US2006059581 or WO1998/044140); event GA21 (maize, herbicidetolerance, Hied as ATCC 209033, described in US2005086719 orWO1998/044140); event GG25 (maize, herbicide tolerance, filed as ATCC209032, described in US2005188434 or WO1998/044140); event GHB119(cotton, insect control-herbicide tolerance, filed as ATCC PTA-8398,described in WO2008/151780); event GHB614 (cotton, herbicide tolerance,filed as ATCC PTA-6878, described in US2010050282 or WO2007/017186);event GJ11 (maize, herbicide tolerance, filed as ATCC 209030, describedin US2005188434 or WO1998/044140); event GM RZ13 (sugar beet, virusresistance, filed as NCIMB-41601, described in WO2010/076212); eventH7-1 (sugar beet, herbicide tolerance, filed as NCIMB 41158 or NCIMB41159, described in US2004172669 or WO2004/074492); event JOPLIN 1(wheat, fungus resistance, not filed, described in US2008064032); eventLL27 (soya bean, herbicide tolerance, filed as NCIMB41658, described inWO2006/108674 or US2008320616); event LL55 (soya bean, herbicidetolerance, filed as NCIMB 41660, described in WO2006/108675 orUS2008196127); event LLcotton25 (cotton, herbicide tolerance, filed asATCC PTA-3343, described in WO2003013224 or US2003097687); eventLLRICE06 (rice, herbicide tolerance, filed as ATCC-23352, described U.S.Pat. No. 6,468,747 or WO2000/026345); event LLRICE601 (rice, herbicidetolerance, filed as ATCC PTA-2600, described in US20082289060 orWO2000/026356); event LY038 (maize, quality trait, filed as ATCCPTA-5623, described in US2007028322 or WO2005061720); event MIR162(maize, insect control, filed as PTA-8166, described in US2009300784 orWO2007/142840); event MIR604 (maize, insect control, not filed,described in US2008167456 or WO2005103301); event MON 15985 (cotton,insect control, filed as ATCC PTA-2516, described in US2004-250317 orWO2002/100163); event MON810 (maize, insect control, not filed,described in US2002102582); event MON863 (maize, insect control, filedas ATCC PTA-2605, described in WO2004/011601 or US2006095986); eventMON87427 (maize, pollination control, filed as ATCC PTA-7899, describedin WO2011/062904); event MON87460 (maize, stress tolerance, filed asATCC PTA-8910, described in WO2009/111263 or US20110138504); eventMON87701 (soya bean, insect control, filed as ATCC PTA-8194, describedin US2009130071 or WO2009/064652); event MON87705 (soya bean, qualitytrait-herbicide tolerance, filed as ATCC PTA-9241, described inUS20100080887 or WO2010/037016); event MON87708 (soya bean, herbicidetolerance, filed as ATCC PTA9670, described in WO2011/034704); eventMON87754 (soya bean, quality feature, filed as ATCC PTA-9385, describedin WO2010/024976); event MON87769 (soya bean, quality trait, filed asATCC PTA-8911, described in US20110067141 or WO2009/102873); eventMON88017 (maize, insect control-herbicide tolerance, filed as ATCCPTA-5582, described in US2008028482 or WO2005/059103); event MON88913(cotton, herbicide tolerance, filed as ATCC PTA-4854, described inWO2004/072235 or US2006059590); event MON89034 (maize, insect control,filed as ATCC PTA-7455, described in WO2007/140256 or US2008260932);event MON89788 (soya bean, herbicide tolerance, filed as ATCC PTA-6708,described in US2006282915 or WO2006/130436); event MS11 (oilseed rape,pollination control-herbicide tolerance, filed as ATCC PTA-850 orPTA-2485, described in WO2001/031042); event MS8 (oilseed rape,pollination control-herbicide tolerance, filed as ATCC PTA-730,described in WO2001/041558 or US2003188347); event NK603 (maize,herbicide tolerance, filed as ATCC PTA-2478, described inUS2007-292854); event PE-7 (rice, insect control, not filed, describedin WO2008/114282); event RF3 (oilseed rape, pollinationcontrol-herbicide tolerance, filed as ATCC PTA-730, described inWO2001/041558 or US2003188347); event RT73 (oilseed rape, herbicidetolerance, not filed, described in WO2002/036831 or US2008070260); eventT227-1 (sugar beet, herbicide tolerance, not filed, described inWO2002/44407 or US2009265817); event T25 (maize, herbicide tolerance,not filed, described in US2001029014 or WO2001/051654); event T304-40(cotton, insect control-herbicide tolerance, filed as ATCC PTA-8171,described in US2010077501 or WO2008/122406); event T342-142 (cotton,insect control, not filed, described in WO2006/128568); event TCI507(maize, insect control-herbicide tolerance, not filed described inUS2005039226 or WO2004/099447); event VIP1034 (maize, insectcontrol-herbicide tolerance, filed as ATCC PTA-3925, described inWO2003/052073); event 32316 (maize, insect control-herbicide tolerance,filed as PTA-11507, described in WO2011/084632); event 4114 (maize,insect control-herbicide tolerance, filed as PTA-11506, described inWO2011/084621).

The plants listed can be treated in accordance with the invention in aparticularly advantageous manner with the inventive active ingredientmixture. The preferred ranges stated above for the mixtures also applyto the treatment of these plants. Particular emphasis is given to thetreatment of plants with the mixtures specifically mentioned in thepresent text.

The control of animal pests, especially of nematodes, by treating theseed of plants has been known for a long time and is the subject ofcontinual improvements. However, in the treatment of seed, a number ofproblems are encountered which cannot always be resolved in asatisfactory manner. Thus, it is desirable to develop methods forprotecting the seed and the germinating plant which at leastsignificantly reduce, or make superfluous, the additional application ofcrop protection agents after sowing or after the emergence of theplants. It is additionally desirable to optimize the amount of activeingredient employed in such a way as to provide maximum protection forthe seed and the germinating plant from attack by animal pests,especially nematodes, but without damaging the plant itself by theactive ingredient used. In particular, methods for the treatment of seedshould also take into consideration the intrinsic insecticidalproperties of transgenic plants in order to achieve optimum protectionof the seed and the germinating plant with a minimum of crop protectionagents being employed.

The present invention therefore also relates especially to a method forthe protection of seed and germinating plants from attack by animalpests, especially by nematodes, and also to a method for increasingyields, by treating the seed with an inventive composition.

The invention likewise relates to the use of the inventive compositionsfor the treatment of seed for protecting the seed and the germinatingplant from animal pests, especially from nematodes, and also forincreasing yields.

The invention further relates to seed which has been treated with aninventive composition for protection from animal pests, especiallynematodes.

One of the advantages of the present invention is that the particularsystemic properties of the inventive compositions mean that treatment ofthe seed with these compositions not only protects the seed itself, butalso the resulting plants after emergence, from animal pests, especiallynematodes. In this manner, the immediate treatment of the crop at thetime of sowing or shortly thereafter can be dispensed with.

It is also considered to be advantageous that the inventive mixtures canalso be used for transgenic seed in particular.

Formulations

The active ingredient combinations can be converted to the customaryformulations such as solutions, emulsions, wettable powders,suspensions, powders, dusts, pastes, soluble powders, granules,suspension-emulsion concentrates, natural and synthetic materialsimpregnated with active ingredient, and microencapsulations in polymericmaterials, for the foliar and soil applications.

These formulations are produced in a known manner, for example by mixingthe active ingredients with extenders, that is, liquid solvents and/orsolid carriers, optionally with the use of surfactants, that is,emulsifiers and/or dispersants, and/or foam formers.

If the extender used comprises water, it is also possible, for example,to use organic solvents as cosolvents. The following are essentiallysuitable as liquid solvents: aromatics such as xylene, toluene oralkylnaphthalenes, chlorinated aromatics or chlorinated aliphatichydrocarbons such as chlorobenzenes, chloroethylenes or methylenechloride, aliphatic hydrocarbons such as cyclohexane or paraffins, forexample mineral oil fractions, mineral and vegetable oils, alcohols suchas butanol or glycol and their ethers and esters, ketones such asacetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone,strongly polar solvents such as dimethylformamide and dimethylsulfoxide, and water.

Suitable solid carriers are:

for example ammonium salts and ground natural minerals such as kaolins,clays, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceousearth, and ground synthetic minerals such as highly disperse silica,alumina and silicates; suitable solid carriers for granules are: forexample crushed and fractionated natural rocks such as calcite, marble,pumice, sepiolite and dolomite, or else synthetic granules of inorganicand organic meals, and granules of organic material such as sawdust,coconut shells, maize cobs and tobacco stalks; suitable emulsifiersand/or foam formers are: for example nonionic and anionic emulsifierssuch as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcoholethers, for example alkylaryl polyglycol ethers, alkylsulfonates, alkylsulfates, arylsulfonates, or else protein hydrolysates: suitabledispersants are: for example lignosulfite waste liquors andmethylcellulose.

Tackifiers such as carboxymethylcellulose and natural and syntheticpolymers in the form of powders, granules or latices, such as gumarabic, polyvinyl alcohol and polyvinyl acetate, or else naturalphospholipids such as cephalins and lecithins and syntheticphospholipids can be used in the formulations. Other possible additivesare mineral and vegetable oils.

It is possible to use colorants such as inorganic pigments, for exampleiron oxide, titanium oxide and Prussian Blue, and organic dyes such asalizarin dyes, azo dyes and metal phthalocyanine dyes, and tracenutrients such as salts of iron, manganese, boron, copper, cobalt,molybdenum and zinc.

The formulations generally contain between 0.1 and 95 wt % of activeingredient, preferably between 0.5 and 90%.

The inventive active ingredient combinations may be present incommercially standard formulations and in the use forms, prepared fromthese formulations, as a mixture with other active ingredients, such asinsecticides, attractants, sterilants, bactericides, acaricides,nematicides, fungicides, growth-regulating substances or herbicides. Theinsecticides include, for example, phosphates, carbamates, carboxylates,chlorinated hydrocarbons, phenylureas and substances produced bymicroorganisms, etc.

Mixing with other known active ingredients such as herbicides or withfertilizers and growth regulators is also possible.

When used as insecticides, the inventive active ingredient combinationsmay additionally be present in their commercially available formulationsand in the use forms, prepared from these formulations, as a mixturewith synergists. Synergists are compounds which enhance the action ofthe active ingredients, without it being necessary for the synergistadded to be active itself.

The active ingredient content of the use forms prepared from thecommercially available formulations may vary within wide limits. Theactive ingredient concentration of the use forms may be from 0.0000001to 95 wt % of active ingredient, preferably between 0.0001 and 50 wt %.

The compounds are employed in a customary manner appropriate for the useforms.

Use Forms

When the active ingredients of the invention are used for controllinganimal pests, more particularly nematodes, the application rates may bevaried within a relatively wide range, depending on the mode ofapplication. The application rate of the active ingredients of theinvention

-   -   when treating parts of plants, such as leaves, is as follows:        from 0.1 to 10 000 g/ha, preferably from 10 to 1000 g/ha, more        preferably from 50 to 300 g/ha (if applied by watering or        chipping, the application rate may even be reduced, especially        if inert substrates such as rock wool or perlite are used);    -   in the treatment of seed is as follows: from 2 to 200 g per 100        kg of seed, preferably from 3 to 150 g per 100 kg of seed, more        preferably from 2.5 to 25 g per 100 kg of seed, very preferably        from 2.5 to 12.5 g per 100 kg of seed;    -   for soil treatment is as follows: from 0.1 to 10 000 g/ha,        preferably from 1 to 5000 g/ha.

These application rates are given only by way of example and withoutlimitation for the purposes of the invention.

The active ingredients anchor compositions of the invention cantherefore be used to protect plants, within a certain period of timeafter treatment, against infestation by animal pests, more particularlynematodes. The period of time within which protection of the plant isbrought about extends in general over 1 to 28 days, preferably over 1 to14 days, more preferably over 1 to 10 days, very preferably over 1 to 7days after the treatment of the plants with the active ingredients, orto up to 200 days after seed treatment.

Foliar Applications

Foliar application is understood to mean the inventive treatment of theplants and plant parts with the active ingredients directly or by actionon the environment, habitat or storage space thereof by the customarytreatment methods, for example by dipping, spraying, vaporizing,nebulizing, scattering, painting and injecting. Plant parts areunderstood to mean all above-ground and below-ground parts and organs ofthe plants, such as shoot, leaf, flower and root, examples includingleaves, needles, steins, stalks, flowers, fruit-bodies, fruits andseeds, and also roots, tubers and rhizomes. The plant parts also includeharvested plants and vegetative and generative propagation material, forexample seedlings, tubers, rhizomes, runners and seeds.

Soil Application

Soil application is understood to mean the control of insects and/orspider mites and/or nematodes by drenching pesticides onto the soil,incorporating them into the soil and m irrigation systems as dropletapplication onto the soil. Alternatively, the inventive activeingredient combinations can be introduced into the site of the plants insolid form (for example in the form of granules). In the case of paddyrice crops, this may also be accomplished by metering the inventiveactive ingredient combinations in a solid application form (for exampleas a granule) into a flooded paddy field.

The invention relates to these application forms to natural (soil) orartificial substrates (for example rock wool, glass wool, quartz sand,pebbles, expanded clay, vermiculite), outdoors or in closed systems(e.g. greenhouses or under film cover) and in annual (e.g. vegetables,potatoes, cotton, beet, ornamental plants) or perennial crops (e.g.citrus plants, fruit, tropical crops, spices, nuts, vines, conifers andornamental plants). It is additionally possible to deploy the activeingredients by the ultra-low-volume method or to inject the activeingredient formulation or the active ingredient itself into the soil.

Seed Treatment

The inventive active ingredient combinations are suitable especially forprotection of seed of any plant variety which is used in agriculture, ingreenhouses, in forests or in horticulture from the aforementionedanimal pests, especially from nematodes. More particularly, the seed isthat of cereals (such as wheat, barley, rye, millet and sorghum, andoats), maize, cotton, soya, rice, potatoes, sunflower, beans, coffee,beet (e.g. sugar beet and fodder beet), peanut, vegetables (such astomato, cucumber, onions and lettuce), lawns and ornamental plants. Ofparticular significance is the treatment of the seed of cereals (such aswheat, barley, rye and oats), maize and rice, and the treatment ofcotton and soya seed.

In the context of the present invention, the inventive composition isapplied on its own or in a suitable formulation to the seed. Preferably,the seed is treated in a state in which it is sufficiently stable thatthe treatment does not cause any damage. In general, treatment of theseed may take place at any point in time between harvesting and sowing.Typically, the seed used has been separated from the plant and freedfrom cobs, shells, stalks, coats, hairs or the flesh of the fruits. Forexample, it is possible to use seed which has been harvested, cleanedand dried to a moisture content of less than 15 wt %. Alternatively, itis also possible to use seed which, after drying, has been treated, forexample, with water and then dried again.

When treating the seed, it generally has to be ensured that the amountof the inventive composition applied to the seed and/or the amount offurther additives is selected such that the germination of the seed isnot adversely affected, and that the resulting plant is not damaged.This must be borne in mind in particular in the ease of activeingredients which may exhibit phytotoxic effects at certain applicationrates.

The inventive active ingredient combinations/compositions can be applieddirectly, i.e. without comprising any further components and withouthaving been diluted. In general, it is preferable to apply thecompositions to the seed in the form of a suitable formulation. Suitableformulations and methods for the treatment of seed are known to theperson skilled in the art and are described, for example, in thefollowing documents: U.S. Pat. Nos. 4,272,417 A, 4,245,432 A, 4,808,430A, 5,876,739 A, US 2003/0176428 A1, WO 2002/080675 A1, WO 2002/028186A2.

The active ingredient combinations usable in accordance with theinvention can be converted to the customary seed dressing productformulations such as solutions, emulsions, suspensions, powders, foams,slurries and other coating compositions for seed, and ULV formulations.

These formulations are prepared in the known manner by mixing the activeingredients or active ingredient combinations with customary additives,for example customary extenders and also solvents or diluents, dyes,wetters, dispersants, emulsifiers, antifoams, preservatives, secondarythickeners, adhesives, gibberellins, and also water.

The colorants which may be present in the seed dressing productformulations usable in accordance with the invention are all colorantswhich are customary for such purposes. Both pigments, which aresparingly soluble in water, and colorants, which are soluble in water,may be used. Examples of dyes include those known by the names RhodamineB, C.I. Pigment Red 112 and C.I. Solvent Red 1.

The wetters which may be present in the seed dressing productformulations usable in accordance with the invention are all substanceswhich are conventionally used for the formulation of active agrochemicalingredients and for promoting wetting. Alkylnaphthalenesulfonates, suchas diisopropyl- or diisobutylnaphthalenesulfonates, can be used withpreference.

Useful dispersants and/or emulsifiers which may be present in the seeddressing product formulations usable in accordance with the inventionare all nonionic, anionic and cationic dispersants which areconventionally used for the formulation of active agrochemicalingredients. Nonionic or anionic dispersants or mixtures of nonionic oranionic dispersants can be used with preference. Suitable nonionicdispersants include, in particular, ethylene oxide/propylene oxide blockpolymers, alkylphenol polyglycol ethers and tristryrylphenol polyglycolethers, and their phosphated or sulfated derivatives. Suitable anionicdispersants are, in particular, lignosulfonates, polyacrylic acid saltsand arylsulfonate/formaldehyde condensates.

The antifoams which may be present in the seed dressing productformulations usable in accordance with the invention are allfoam-suppressing substances conventionally used for the formulation ofactive agrochemical ingredients. Silicone antifoams and magnesiumstearate can be used with preference.

The preservatives which may be present in the seed dressing productformulations usable in accordance with the invention are all substanceswhich can be employed in agrochemical compositions for such purposes.Examples include dichlorophen and benzyl alcohol hemiformal.

The secondary thickeners which may be present in the seed dressingproduct formulations usable in accordance with the invention are allsubstances which can be employed in agrochemical compositions for suchpurposes. Cellulose derivatives, acrylic acid derivatives, xanthan,modified clays and finely divided silica are preferred.

The adhesives which may be present in the seed dressing productformulations usable in accordance with the invention are all customarybinders which can be employed in seed dressing products. Preference isgiven to polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol andtylose.

The gibberellins which may be present in the seed dressing productformulations usable in accordance with the invention are preferably thegibberellins A1, A3 (=gibberellic acid), A4 and A7, particularpreference being given to using gibberellic acid. The gibberellins areknown (cf. R. Wegler “Chemie der Pflanzenschutz-undSchadlingsbekämpnmgsmittel” [Chemistry of Plant Protectants andPesticides], Vol. 2, Springer Verlag, 1970, pp. 401-412).

The seed dressing product formulations usable in accordance with theinvention can be employed either directly or after preceding dilutionwith water for the treatment of a wide range of seeds. For instance, theconcentrates or the formulations obtainable therefrom by dilution withwater can be used to dress the seed of cereals, such as wheat, barley,rye, oats and triticale, and the seed of maize, rice, rape, peas, beans,cotton, soya, sunflowers and beet, or else a wide variety of differentvegetable seeds. The seed dressing product formulations usable inaccordance with the invention or the dilute preparations thereof canalso be used to dress seed of transgenic plants. In this context,additional synergistic effects may also occur as a consequence of theinteraction with the substances formed by expression.

Useful apparatus which can be used to treat seed with the seed dressingproduct formulations usable in accordance with the invention, or withthe preparations prepared therefrom by addition of water, is all mixingapparatus which can typically be used to dress seed. Specifically, theseed dressing procedure is to place the seed into a mixer, add theamount of seed dressing product formulation desired in each case, eitheras such or after preceding dilution with water, and mix until theformulation has been distributed homogeneously on the seed. Ifappropriate, this is followed by a drying process.

The application rate of the seed dressing product formulations usable inaccordance with the invention can be varied within a relatively widerange. It is guided by the particular content of the active ingredientsin the formulations and by the seed. The application rates of the activeingredient combinations are generally between 0.001 and 50 g perkilogram of seed, preferably between 0.01 and 25 g per kilogram of seed.

Calculation Formula for the Mortality of a Combination of Two ActiveIngredients

The anticipated effect of a given combination of two active ingredientsmay be calculated (cf. Colby, S. R., “Calculating Synergistic andAntagonistic Responses of Herbicide Combinations”, Weeds 15, pages20-22, 1967) as follows:

-   -   if    -   X is the mortality, expressed in % of the untreated control,        when active ingredient A is used in an application rate of m        ppm, or m g/ha    -   Y is the mortality, expressed in % of the untreated control,        when active ingredient B is used in an application rate of n        ppm, or n g/ha    -   E is the mortality, expressed in % of the untreated control,        when active ingredients A and B are used at application rates of        m and n ppm or of m and n g/ha,    -   then

$E = {X + Y - {\frac{X \cdot Y}{100}.}}$

If the actual insecticide mortality is greater than calculated, then thecombination is superadditive in its kill—that is, there is a synergisticeffect. In this case the mortality actually observed must be greaterthan the value for the expected mortality (E) calculated on the basis ofthe formula given above.

EXAMPLE 1 Myzus Test (Spray Treatment) Solvent: 78 Parts by Weight ofAcetone

-   -   1.5 parts by weight of dimethylformamide        Emulsifier: 0.5 part by weight of alkylaryl polyglycol ether

A suitable preparation of active ingredient is prepared by mixing onepart by weight of active ingredient with the staled amounts of solventand emulsifier and diluting the concentrate with emulsifier-containingwater to the desired concentration. A suitable suspension of biologicalagent is prepared by dissolving the cells, spores or viruses inemulsifier-containing water in the desired concentration.

Chinese cabbage (Brassica pekinensis) leaf disks infested by all stagesof the green peach aphid (Myzus persicae) are sprayed with an activeingredient and/or biological agent preparation in the desiredconcentration.

After the desired lime, the effect in % is ascertained. Here, 100% meansthat all of the aphids have been killed; 0% means that no aphids havebeen killed. The mortality figures determined are used for calculationaccording to the Colby formula (see sheet 1).

In this test, the following combination of fluopyram with a furtheractive ingredient or with a biological agent in accordance with thepresent specification gave a synergistically boosted activity incomparison to the substances employed individually:

TABLE 1-1 Myzus persicae test Active ingredient/biological Concentrationagents g ai/ha Mortality in % after 1^(d) Fluopyram 1000 0 5●0 ●Imicyafos    67.5 0 found* calc.** Fluopyram + imicyafos 1000 + 67.5 100  0 Pyrethrum  100 80  found* calc.** Fluopyram + pyrethrum 1000 +100  100  80 Fluensulfone 2000 0 found* calc.** Fluopyram + fluensulfone 500 + 2000 90  0 Paecilomyces lilacinus 5000 ● strain 251 found*calc.** Fluopyram + Paecilomyces 1000 + 5000 70  0 lilacinus strain 251Bacillus amyloliquefaciens 2000 ● strain FZB 42 found* calc.**Fluopyram + Bacillus 1000 + 2000 90  0 amyloliquefaciens Cydia pomonellagranulosis 1000 0 virus (CpGV) found* calc.** Fluopyram + Cydiapomonella 1000 + 1000 70  ● granulosis virus (CpGV)

TABLE 1-2 Myzus persicae test Active ingredient/biological Concentrationagents g ai/ha Mortality in % after 6^(d) Fluopyram 1000 0  500 0Bacillus thuringiensis subsp. 1000 0 tenebrionis found* calc.**Fluopyram. + Bacillus 1000 + 1000 80  0 thuringiensis subsp. tenebrionisAzadirachtin 10● 0 found* calc.** Fluopyram + azadirachtin 1000 + 100 70  0 Metschnikowia fructicola 1000 0 found* calc.** Fluopyram +Metschnikowia  500 + 3000 90  0 fructicola *found = insecticidal actionfound, **calc. = action calculated by the Colby formula

EXAMPLE 2

Spodoptera frugiperda Test (Spray Treatment)Solvent: 78.0 parts by weight of acetone

-   -   1.5 parts by weight of dimethylformamide        Emulsifier 0.5 part by weight of alkylaryl polyglycol ether

A suitable preparation of active ingredient is prepared by mixing onepart by weight of active ingredient with the stated amounts of solventand emulsifier and diluting the concentrate with emulsifier-containingwater to the desired concentration.

Maize (Zea mays; corn) leaf disks are sprayed with an active ingredientpreparation of the desired concentration and, after drying off, arepopulated with caterpillars of the army worm (Spodoptera frugiperda).

After the desired time, the effect in % is ascertained. Here, 100% meansthat all of the caterpillars have been killed, 0% means that nocaterpillar has been killed. The mortality figures determined are usedfor calculation according to the Colby formula (see sheet 1).

In this test, the following combination of fluopyram and a furtheractive ingredient in accordance with the present specification gave asynergistically boosted activity in comparison to the active ingredientsemployed individually:

TABLE 2 Spodoptera frugiperda test Active ingredient/biologicalConcentration agents g ai/ha Mortality in % after 2^(d) Fluopyram 1000 0 Pyrethrum 100 33 found* calc.** Fluopyram + pyrethrum 1000 + 100 5033 * found = insecticidal action found, ** calc. = action calculated bythe Colby formula

EXAMPLE 3 Seed Treatment—Cotton Emergence Test

Seed of cotton (Gossypium hirsutum) is mixed with the desired amount ofactive ingredient and spores and also water. After drying, 25 seedgrains in each case are sown in pots filled with sandy loam.

After 2 days, the effect in % is ascertained on the basis of the cottonplants that have emerged.

The following combinations of fluopyram and biological agents gave abetter emergence rate in comparison to the substances employedindividually and to the untreated control:

TABLE 3 Cotton emergence Emergence in % in Active ingredient/biologicalConcentration comparison to agents g ai/kg seed untreated controlControl (untreated seed) 100 Fluopyram 1 133 0.5 100 Bacillus subtilisstrain GB 03 0.078 158 Fluopyram + B. subtilis 0.5 + 0.078 288 strain GB03 Bacillus amyloliquefaciens 0.15 163 strain FZB 42 0.075 158Fluopyram. + B. amyloliquefaciens 1.0 + 0.15  225 strain FZB 42 0.5 +0.075 221 * found = insecticidal action found, ** calc. = actioncalculated by the Colby formula

EXAMPLE 4

Meloidogyne incognita TestSolvent: 125.0 parts by weight of acetone

A suitable preparation of active ingredient is prepared by mixing onepart by weight of active ingredient with the stated amounts of solventand diluting the concentrate with water to the desired concentration. Aspore suspension is prepared by diluting the spores with water to thedesired concentration.

Vessels are filled with sand, active ingredient solution, Meloidogyneincognita egg-and-larvae suspension, and lettuce seeds. The lettuceseeds germinate and the seedlings develop. The galls develop on theroots.

After the desired time, the nematicidal effect is determined on thebasis of gall formation in %. Here, 100% means that no galls have beenfound; 0% means that the number of galls on the treated plantscorresponds to the untreated control. The figures ascertained are usedfor calculation according to the Colby formula (see sheet 1).

In this test, the following combination of fluopyram and biologicalagents in accordance with the present specification gave asynergistically boosted activity in comparison to the active ingredientsemployed individually:

TABLE 4 Meloidogyne incognita test Active ingredient/biologicalConcentration agents in ppm Mortality in % after 21^(d) Fluopyram ●.00050 Metarhizium anisopliae 5 ● strain F52 found* calc.** Fluopyram + M.anisopliae 0.0005 + 5 80  0 strain F52 *found = insecticidal actionfound, **calc. = action calculated by the Colby formula

EXAMPLE 5

Glycine max—Growth Promotion in Combination with Mycorrhiza

Seed of soya beans (Glycine max) is mixed with the desired amount ofactive ingredient in water. After drying, the seeds are sown in potsfilled with sand and perlite (1:1). For inoculation with arbuscularmycorrhiza fungi, the sand-perlite mixture is mixed beforehand with theMycorrhiza inoculum (AMykor GmbH; Germany) in a concentration of 25ml/L. The seed is covered with 3 cm of Lecaton (expanded clay).

Over the following 44 days, the plants are cultivated m a greenhouse ingood growth conditions. The pots are watered with a nutrient solution(Hoagland and Arnon, 1950, half-concentrated solution) with a lowphosphate concentration (20 μM).

The untreated control plants are cultured without arbuscular mycorrhizafungi, but under the same conditions.

The growth-promoting effect on shoot and roots is ascertained via theweight of the fresh roots of the treated plant in comparison to theuntreated control.

The following combination of active ingredient and biological agentsgives increased root growth in comparison to the ingredients and agentsapplied individually, and to the control:

TABLE 5 Plant growth of soya bean Root weight in % in Activeingredient/biological Concentration comparison to agents mg/seed grainuntreated control Control — 100 Fluopyram 0.1 116.90 Arbuscularmycorrhiza fungus — 133.21 Fluopyram + arbuscular 0.1 137.91 mycorrhizafungus

1. An active ingredient combination comprising (I) fluopyram or anN-oxide thereof and (II) Rhizobium spp.
 2. A method for controlling oneor more animal pests, comprising applying the active ingredientcombination of claim 1 to leaves, flowers, stems and/or seed of a plantto be protected, to an animal pest and/or a habitat thereof, and/or tosoil.
 4. The active ingredient combination of claim 1, comprisingsynergistically effective amounts of the fluopyram and Rhizobium spp. 5.A process for preparing a composition, comprising mixing the activeingredient combination of claim 1 with at least one extender and/orsurfactant.
 6. A seed having applied thereto the active ingredientcombination of claim
 1. 7. A method for treating seed comprisingcontacting said seed with the active ingredient combination of claim 1.8. A method for treating soil and/or an artificial substrate comprisingcontacting said soil and/or substrate with the active ingredientcombination of claim
 1. 9. A method for controlling nematodes that arein soil, comprising contacting the soil with the active ingredientcombination of claim
 1. 10. The active ingredient combination of claim1, wherein the weight ratio of fluopyram to said Rhizobium spp. is 500:1to 1:500.
 11. The active ingredient combination as defined in claim 1,wherein the weight ratio of fluopyram to said Rhizobium spp. is 125:1 to1:125.
 12. The active ingredient combination as defined in claim 1,wherein the weight ratio of fluopyram to said Rhizobium spp. is 25:1 to1:25.